Laser treatment for peri-implantitis using two different wavelengths

An Evaluation Of Effectiveness Of A Combined Er:YAG And Nd:YAG Laser Protocol For Treatment Of Peri-Implantitis: A Randomized Controlled Trial

Not applicable Interventional Cooperativa de Ensino Superior, Politécnico e Universitário · NCT03819075

This study is testing whether a special laser treatment for gum disease around dental implants works better than regular cleaning methods for patients with peri-implantitis.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment62 (estimated)
Ages18 Years and up
SexAll
SponsorCooperativa de Ensino Superior, Politécnico e Universitário Academic / other
Locations1 site (Porto)
Trial IDNCT03819075 on ClinicalTrials.gov

What this trial studies

This study evaluates the effectiveness of a combined Er:YAG and Nd:YAG laser treatment protocol for patients diagnosed with peri-implantitis, comparing it to standard mechanical treatment. Participants will receive either the laser treatment or conventional care in a randomized controlled setup. The study aims to assess clinical outcomes over a follow-up period of at least 12 months, ensuring participants adhere to post-treatment care and hygiene recommendations.

Who should consider this trial

Good fit: Ideal candidates are individuals with at least one dental implant affected by peri-implantitis who can commit to follow-up visits.

Not a fit: Patients with serious systemic diseases, pregnancy, or those currently using certain medications may not benefit from this study.

Why it matters

Potential benefit: If successful, this treatment could provide a more effective and less invasive option for managing peri-implantitis, potentially improving patient outcomes.

How similar studies have performed: Other studies have shown promising results with laser treatments for peri-implantitis, suggesting potential efficacy of this combined approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* at least one implant with peri-implantitis
* no serious mobility of the implants
* written informed consent of the voluntary participant in the study
* availability of participant for control visits for a follow-up of at least 12 months without interruptions

Exclusion Criteria:

* serious systematic disease
* pregnancy
* current use of photosensitive drugs, bisphosphonate medication or antibiotics
* patients who do not want to follow post treatment recommendation of oral hygiene and follow-up visits

Where this trial is running

Porto

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Peri-ImplantitislaserEr:YAGNd:YAGperiimplantitisrandomized controlled trial
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.