Laser ablation treatment for prostate cancer using MRI and ultrasound guidance

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial is an observational registry aimed at recording the outcomes of patients treated with targeted laser ablation for biopsy-confirmed prostate cancer. It evaluates short, intermediate, and long-term results, focusing on procedure-related tolerability, perioperative adverse events, oncological control, and functional outcomes such as urinary and sexual function. The study will assess the effectiveness of MRI and ultrasound fusion in guiding the laser ablation process and will monitor for cancer recurrence and metastasis over time.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Men between 50 and 65 years of age with a clinical diagnosis of prostate cancer with Low or Intermediate risk prostate cancer, and \<50% positive core rate by prostate lobe
* Men older than 65 years of age with clinical diagnosis of prostate cancer \<50% positive core rate by prostate lobe
* Absence of extra-capsular extension
* Absence of seminal vesicle invasion
* Absence of regional or distant metastatic disease
* Multiparametric MRI of the prostate performed either before the biopsy or \>10 weeks after prostate biopsy
* Treated with Cryotherapy of the prostate
* Treatment based on co-registration between MP-MRI and Prostate Ultrasound

Exclusion Criteria:

* Prior treatment of prostate cancer in the form of surgery.
* Performance status greater than 0 based on ECOG criteria
* Mental status impairment

Where it's running

• Urological Research Network
  Miami Lakes, Florida, United States Recruiting

Study contacts

• Principal investigator: Fernando J Bianco, Md — Urological Research Network
• Study coordinator: Cielo D Guerra, Bs
• Email: CIELO@BESTUROLOGY.NET
• Phone: 305-515-9887

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.