Laparoscopic surgery to improve immune function in cirrhosis patients

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the effects of laparoscopic splenectomy and azygoportal disconnection on immune function in patients with liver cirrhosis. Patients diagnosed with cirrhosis and experiencing splenomegaly will undergo the surgical procedure, followed by a standardized treatment plan and monitoring of immune-related indicators at various intervals post-surgery. The goal is to determine if this surgical intervention can enhance immune function and improve overall patient prognosis.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* A clinical, radiological or histologic diagnosis of cirrhosis of any etiology
* Splenomegaly with secondary hypersplenism
* gastroesophageal variceal bleeding
* Informed consent to participate in the study

Exclusion Criteria:

* Hepatocellular carcinoma or any other malignancy,
* Child-Pugh grade C
* Recent peptic ulcer disease
* History of Hemorrhagic stroke
* Pregnancy.
* Uncontrolled Hypertension
* Human immunodeficiency virus (HIV) infection

Where it's running

• Clinical Medical College, Yangzhou University
  Yangzhou, Jiangsu, China Recruiting

Study contacts

• Study coordinator: Guo-Qing Jiang, MD
• Email: jgqing2003@hotmail.com
• Phone: +8651487373382

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.