Laminoplasty for cervical spine issues using MRI techniques
Feasibility and Clinical Applicability of Surgical Segments Choice for Laminoplasty in Multilevel Cervical Spondylotic Myelopathy Guided by Modified K-line and Modified SC-line in MRI
This study is testing how certain MRI techniques can help doctors make better decisions about surgery for patients with neck problems caused by spinal cord issues.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 300 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Affiliated 2 Hospital of Nantong University Academic / other |
| Locations | 1 site (Nantong, Jiangsu) |
| Trial ID | NCT06478485 on ClinicalTrials.gov |
What this trial studies
This observational study aims to investigate the impact of modified K-line and modified SC-line on surgical decision-making for patients with multilevel cervical spondylotic myelopathy (MCSM). It will collect MRI data from patients undergoing laminoplasty (LAMP) surgery to determine how these imaging techniques can predict surgical outcomes and decompression effectiveness. The study focuses on patients with specific MRI characteristics that may influence their prognosis post-surgery. By analyzing these factors, the study seeks to enhance the understanding of optimal surgical approaches for MCSM.
Who should consider this trial
Good fit: Ideal candidates are patients diagnosed with multilevel cervical spondylotic myelopathy who are scheduled for laminoplasty surgery and have specific MRI characteristics.
Not a fit: Patients with previous cervical spine surgery or other neurological disorders may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could improve surgical outcomes for patients with multilevel cervical spondylotic myelopathy by refining surgical decision-making.
How similar studies have performed: While this approach is novel in its combination of imaging techniques for surgical decision-making, similar studies have shown promise in improving surgical outcomes in related conditions.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: (1) Diagnosis of MCSM confirmed by two spine surgeons with MRI examination and clinic signs; (2) More than 2 level lesions and/or spinal stenosis in MRI, underwent LAMP surgery; (3) Available for both preoperative and follow-up imaging data and clinical data, including sex, age, clinical symptoms, Japanese Orthopedic Association (JOA) score, Visual Analog Scale (VAS) score, Neck Disability Index(NDI) score and MRI data. Exclusion Criteria: (1) Previous cervical spine surgery; (2) Diagnosis of tumor, central cord syndrome, infection or other acute traumatic injuries; (3) Diagnosed neurological disorders Parkinson's disease, polio, multiple sclerosis, or other central and peripheral nervous system diseases).
Where this trial is running
Nantong, Jiangsu
- The Second Affiliated Hospital of Nantong University — Nantong, Jiangsu, China (Recruiting)
Study contacts
- Principal investigator: Zhiming Cui, Professor — Second Affiliated Hospital of Nantong University
- Study coordinator: Chunshuai Wu, Doctor
- Email: wcsspine@ntu.edu.cn
- Phone: +8613861989196
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.