Lacrifill for contact lens wearers with dry eye who can't wear lenses comfortably

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a Phase 4, single-arm interventional study giving Lacrifill eye drops to adult contact lens wearers with dry eye over a two- to three-month period to measure comfort and ocular surface signs. Eligible participants are over 21, currently wear contact lenses, have prior dry eye treatment, CLDEQ-8 ≥12, Schirmer anesthetized ≤10, and corneal staining NEI ≥1, and may remain on stable permitted medications. The protocol tracks contact lens wearing time, symptom scores, Schirmer testing, and corneal staining without a randomized control group. The trial is sponsored by Vision Innovation Centers of Pennsylvania in collaboration with Nordic Pharma and is conducted at Eye Care Specialists in Kingston, PA.

Why it matters

Who can join: the full rules

Inclusion Criteria

* \>21 years of age
* Contact lens wearer
* Previous Dry Eye Treatment
* Be on a stable dose of antihistamines/Birth Control Medication and Lifitegrast and cyclosporine.
* Schrimers Anesthetized less than or equal to 10
* CLDEQ-8 greater than or equal to 12
* Corneal Staining NEI grading scale greater than or equal to 1

Exclusion Criteria:

* Known allergy to Hyaluronic Acid
* Current topical ophthalmic drops other than dry eye treatment
* Uncontrolled Diabetes
* Diabetic Retinopathy
* Pregnancy or Lactating
* Corneal Surgery (except Refractive)
* Corneal Scars
* Keratoconus
* Ocular Herpetic Keratitis

Where it's running

• Eye Care Specialists
  Kingston, Pennsylvania, United States Recruiting

Study contacts

• Study coordinator: Patti Myers, COT
• Email: patti.myers@vipeyes.com
• Phone: 5707145910

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.