Ketamine improves pain relief and mood in chronic pain patients

Ketamine Analgesia Enhances Functional Quality and Mood in Chronic Pain Patients

Observational Salem Anaesthesia Pain Clinic · NCT05985811

This study is testing whether Ketamine injections can help people with chronic pain and mood disorders feel better both physically and emotionally.

Quick facts

Study typeObservational
Enrollment500 (estimated)
Ages20 Years to 99 Years
SexAll
SponsorSalem Anaesthesia Pain Clinic Academic / other
Locations1 site (Surrey, British Columbia)
Trial IDNCT05985811 on ClinicalTrials.gov

What this trial studies

This observational study investigates the effects of Ketamine injections on chronic pain patients who also suffer from mood disorders. It collects pre-injection and post-injection data on pain, sleep, anxiety, and depression using validated scales. The study aims to determine if improved analgesia from Ketamine can lead to significant enhancements in mood and overall well-being. Data analysis will utilize various statistical methods to assess the significance of changes in patient scores.

Who should consider this trial

Good fit: Ideal candidates include adult chronic pain patients who also have mood disorders and are compliant with treatment.

Not a fit: Patients with severe cognitive disorders, major neuropsychiatric disorders, or those using substances like cannabis or stimulants may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could provide chronic pain patients with improved pain management and enhanced mood stability.

How similar studies have performed: While the use of Ketamine for pain management is gaining attention, this specific observational approach focusing on mood improvement in chronic pain patients is relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* adult chronic pain patients
* associated mood disorder
* good treatment compliance
* associated chronic insomnia
* regular ketamine pain therapy injection
* consent for clinical record quality assurance review

Exclusion Criteria:

* severe cognitive disorder
* inability to provide consent
* major neuropsychiatric disorder
* cannabis use
* stimulant use
* substance abuse
* poor treatment compliance
* lack of ketamine pain therapy injection

Where this trial is running

Surrey, British Columbia

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Mood DisorderOpioidMood InsomniaMood therapy
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.