Clinical trial Recruiting at 1 site Interventional Ages 18 to 75

Just-in-Time Practices to Prevent Weight Regain from Stopping Your Progress

Official title: Testing Just-in-Time Adaptive Interventions (JITAIs) to Prevent Goal Disengagement in Response to Weight Regain

Run by ORI Community and Evaluation Services · NCT07708064 · Data updated 2026-11-12

This trial tests whether sending brief mindfulness and self-compassion exercises right after weight regain or a missed weigh-in helps people stick with their long-term weight goals.

Quick facts

Study typeInterventional
Ages18 Years to 75 Years
SexAll
Enrollment120 (estimated)
SponsorORI Community and Evaluation Services
Academic / other
Locations1 site (Springfield, Oregon)
StatusRecruiting
StartedJuly 14, 2026
Main results expectedDecember 31, 2027
Study endsDecember 31, 2027
Registry record updatedNovember 10, 2026
Trial IDNCT07708064 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults 18-75 with BMI 25-50 kg/m2 who recently weighed at least 3% less than their highest weight in the past 3 years and want to maintain or further lose weight.

Probably not a fit

Individuals who do not experience weight regain or who cannot engage with a smartphone app may see little benefit.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Participants with overweight or obesity who have recently maintained a loss are randomized to receive either immediate short exercises via a smartphone app after weight regain or missed weigh-ins, or weekly reminders of standard weight-control strategies. The intervention uses mindfulness, acceptance, and self-compassion techniques to sustain motivation. The study aims to see if this timely, adaptive support improves weight maintenance compared to routine reminders.

Why it matters

Potential benefit: If successful, the approach could help people maintain weight loss by reducing discouragement after weight regain.

How similar studies have gone: Earlier approaches using timely behavioral prompts have shown promise in supporting weight management, but this specific JITAI approach for weight regain is relatively new.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Ages 18-75 years
* BMI of 25-50 kg/m2
* Current weight is 3% lower than their highest weight in the past 3 years
* Desire to maintain their weight or lose more
* Ability to engage in PA, as defined as being able to walk two full city blocks without stopping
* Smartphone and Internet access
* Successful completion of all enrollment procedures
* Ability to attend a workshop(s) on a Monday or Tuesday evening

Exclusion Criteria:

* History of bariatric surgery
* History of being diagnosed with an eating disorder
* Currently pregnant, breastfeeding, or planning to become pregnant in the next 24 months
* Enrolled in another formal weight loss/weight maintenance program
* Currently taking a GLP-1 medication.

Where it's running

  • Oregon Research Institute Community and Evaluation Services
    Springfield, Oregon, United States
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.