Clinical trial Recruiting at 2 sites Phase 4 Interventional Ages 22 to 65

Jawline and neck treatment satisfaction in adults

Official title: A Prospective, Open-label Study to Evaluate Subject Satisfaction and Psychosocial Outcomes After Treatment of Jawline and Neck With BOTOX® Cosmetic and JUVÉDERM® Products

Run by AbbVie · NCT07794891 · Data updated 2026-11-12

This study tests whether a combination of injectables for the jawline and neck increases participant satisfaction in adults with concerns about jawline and neck appearance.

Quick facts

PhasePhase 4
Study typeInterventional
Ages22 Years to 65 Years
SexAll
Enrollment100 (estimated)
SponsorAbbVie
Industry-sponsored
Locations2 sites (Vancouver, British Columbia and 1 other locations)
StatusRecruiting
StartedSeptember 9, 2026
Main results expectedJune 2027
Study endsJune 2027
Registry record updatedOctober 8, 2026
Trial IDNCT07794891 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults with moderate or severe transverse neck lines, reduced jawline definition, or prominent platysma who have no contraindications to botulinum toxin or dermal fillers.

Probably not a fit

Individuals with contraindications to BOTOX or dermal fillers, or those unlikely to experience meaningful changes in appearance or satisfaction may not benefit.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This interventional study enrolls adults with moderate to severe jawline and neck concerns to receive selected cosmetic products (onabotulinumtoxinA, SKINVIVE, VOLUX, VOLUMA) in the jaw area and neck. It aims to measure changes in satisfaction with lower face, jawline, and skin appearance, along with psychological well-being related to appearance. Participants will have clinic visits for medical assessments, vital signs, examinations, safety checks, and questionnaires to track outcomes and adverse events. The study follows eligibility criteria to identify appropriate candidates and will assess both aesthetic changes and patient-reported outcomes. Investigational products will be administered per standard clinical practice under supervision at two Canadian sites.

Why it matters

Potential benefit: If successful, participants may experience improved jawline definition and neck appearance with associated increased satisfaction and quality of life.

How similar studies have gone: Prior cosmetic studies using botulinum toxin and dermal fillers for facial contouring have shown variable satisfaction improvements; this study builds on that approach in a targeted jawline/neck population.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Moderate or severe transverse neck lines based on investigator's live assessment
* Moderate or severe loss of jawline definition based on investigator's live assessment.
* Moderate or severe platysma prominence based on investigator's live assessment.

Exclusion Criteria:

* History of or current medical condition that may put the subject at increased medical risk with exposure to BOTOX, or any other condition that might interfere with neuromuscular function.
* History of or current symptoms of dysphagia.
* History of severe allergies manifested by a history of anaphylaxis or history or presence of multiple severe allergies.
* History of hypersensitivity or allergy to any botulinum toxin serotype, Streptococcal or gram-positive bacterial proteins, lidocaine, HA products, any other excipients or constituents of the study drug, device, and/or other products in the same class.
* History of or tendency for keloid formation, hyperpigmentation, or hypertrophic scarring.

Where it's running

  • Humphrey & Beleznay Cosmetic Dermatology /ID# 282598
    Vancouver, British Columbia, Canada
    Recruiting
  • Sweat Clinics Of Canada /ID# 281845
    Toronto, Ontario, Canada
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Browse more
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.