IV lidocaine for headaches after non‑traumatic subarachnoid hemorrhage

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This prospective observational project will give adults with non‑traumatic subarachnoid hemorrhage an intravenous lidocaine infusion as part of their headache treatment while collecting data on pain and safety. Patients will report numeric pain scores every two hours while awake for up to seven days, and clinicians will monitor for vasospasm as part of routine care. Inclusion requires age over 18, a Hunt and Hess score of 3 or less, and the ability to communicate pain scores; significant cardiac disease, arrhythmia, seizures, or prior lidocaine allergy exclude participants. The design is non-randomized and descriptive, so results will show safety and pain trends rather than prove definitive causation.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients \> 18 years;
* Have a favorable neurological status defined as Hunt and Hess score ≤ 3 (as it accounts for patient awareness);
* Can communicate numeric pain scores;
* Are diagnosed with non-traumatic subarachnoid hemorrhage

Exclusion Criteria:

* The patient is diagnosed with traumatic subarachnoid hemorrhage;
* If the patient is \< 18 years of age;
* If numeric pain scores could not be captured for \> 3 days of hospitalization;
* If the patient had a prior aneurysm;
* Chronic pain not associated with non-traumatic subarachnoid hemorrhage diagnosis;
* A disability before the stroke (\> 2 on modified Rankin Scale score);
* A Hunt and Hess score \> 3;
* Contraindications to lidocaine (significant cardiac disease, arrhythmia, seizures, previous allergic reaction to lidocaine

Where it's running

• Ascension Via Christi St. Francis
  Wichita, Kansas, United States Recruiting

Study contacts

• Principal investigator: Fernando Salgado, MD — University of Kansas Medical Center
• Study coordinator: William L Krogman, MS
• Email: wkrogman@kumc.edu
• Phone: 316-268-6156

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.