Using CCTA to improve management of stable chest pain
Official title: Improving the Clinical Management of Stable Chest Pain Based on Imaging: a Registry of Computed Tomography Coronary Angiography
Run by Tianjin Chest Hospital · NCT04691037 · Data updated 2026-11-12
This study is testing if using a special heart scan called CCTA can help doctors better manage stable chest pain and reduce serious heart problems for patients suspected of having blocked arteries.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 50000 (estimated) |
| Sponsor | Tianjin Chest Hospital Academic / other |
| Locations | 4 sites (Beijing, Beijing Municipality and 3 other locations) |
| Status | Recruiting |
| Started | January 1, 2016 |
| Main results expected | January 1, 2030 |
| Study ends | January 1, 2030 |
| Registry record updated | March 28, 2024 |
| Trial ID | NCT04691037 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are symptomatic patients aged 18 and older with stable chest pain suspected of obstructive coronary artery disease.
✕Probably not a fit
Patients with acute coronary syndromes, previous coronary artery disease or revascularization, and certain heart conditions will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study aims to enroll patients referred for coronary computed tomography angiography (CCTA) to assess stable chest pain suspected of obstructive coronary artery disease (CAD). Patients will undergo CCTA following established guidelines, and the imaging data will be analyzed using various post-processing software to gather comprehensive anatomical, functional, and histological information. The goal is to determine if CCTA can enhance clinical management, reduce major adverse cardiovascular events (MACE), and improve decision-making regarding further investigations and treatments.
Why it matters
Potential benefit: If successful, this approach could lead to better management of stable chest pain and potentially reduce the risk of serious cardiovascular events.
How similar studies have gone: Other studies have shown that CCTA can provide valuable insights for managing coronary artery disease, indicating a promising approach.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * symptomatic patients with SCP suspected of obstructive CAD. * referred for CCTA for the assessment of SCP. * ≥18 years of age. * signed informed consent. Exclusion Criteria: * acute coronary syndromes * previous CAD or coronary revascularization * nonsinus rhythm * cardiomyopathy, valvular disease, congenital heart disease or left cardiac insufficiency because of other reasons
Where it's running
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Beijing Chaoyang Hospital
Beijing, Beijing Municipality, China Recruiting -
Hebei Petrochina Central Hospital
Langfang, Hebei, China Recruiting -
Tianjin Chest Hospital
Tianjin, Tianjin Municipality, China Recruiting -
Tianjin First Central Hospital
Tianjin, Tianjin Municipality, China Recruiting
Study contacts
- Study coordinator: Jia Zhou
- Email: zhoujiawenzhang@126.com
- Phone: +8615522485560
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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CCTA-Guided CABG vs CAG-Guided CABG
This study tests whether planning CABG with a non-invasive CCTA scan works as well as planning with the standard invasive CAG approach for people with blocked heart arteries.
-
Bypass surgery versus stents for people with weak heart pumping and blockages in multiple coronary arteries
This trial tests whether bypass surgery (CABG) or stents (PCI) lead to better survival, fewer major heart problems, and improved quality of life for adults with reduced left ventricular function (LVEF ≤40%) and multivessel coronary disease.
-
Using transthoracic echocardiography to improve care for stable chest pain
This project will test whether adding transthoracic echocardiography (TTE) helps doctors make better decisions and lowers major heart problems in adults with stable chest pain suspected to be from coronary artery disease.
-
Comparing heart imaging techniques for coronary artery disease
This study is testing if a new heart imaging method can better identify problems in patients suspected of having coronary artery disease compared to a traditional imaging technique.
-
Short-term high-dose rosuvastatin effects on coronary plaque using photon-counting CT
This trial tests whether a short course of intensified rosuvastatin (40 mg) changes coronary plaque composition and flow on photon‑counting coronary CT in statin‑naive adults with stable chest pain and mild atherosclerosis.
-
AI tools for predicting high-risk coronary plaques
This study is testing a new AI tool to see if it can better predict dangerous plaque buildup in the arteries of people with heart disease.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.