Clinical trial Recruiting at 4 sites Observational Ages 18 and up

Using CCTA to improve management of stable chest pain

Official title: Improving the Clinical Management of Stable Chest Pain Based on Imaging: a Registry of Computed Tomography Coronary Angiography

Run by Tianjin Chest Hospital · NCT04691037 · Data updated 2026-11-12

This study is testing if using a special heart scan called CCTA can help doctors better manage stable chest pain and reduce serious heart problems for patients suspected of having blocked arteries.

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment50000 (estimated)
SponsorTianjin Chest Hospital
Academic / other
Locations4 sites (Beijing, Beijing Municipality and 3 other locations)
StatusRecruiting
StartedJanuary 1, 2016
Main results expectedJanuary 1, 2030
Study endsJanuary 1, 2030
Registry record updatedMarch 28, 2024
Trial IDNCT04691037 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are symptomatic patients aged 18 and older with stable chest pain suspected of obstructive coronary artery disease.

Probably not a fit

Patients with acute coronary syndromes, previous coronary artery disease or revascularization, and certain heart conditions will not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to enroll patients referred for coronary computed tomography angiography (CCTA) to assess stable chest pain suspected of obstructive coronary artery disease (CAD). Patients will undergo CCTA following established guidelines, and the imaging data will be analyzed using various post-processing software to gather comprehensive anatomical, functional, and histological information. The goal is to determine if CCTA can enhance clinical management, reduce major adverse cardiovascular events (MACE), and improve decision-making regarding further investigations and treatments.

Why it matters

Potential benefit: If successful, this approach could lead to better management of stable chest pain and potentially reduce the risk of serious cardiovascular events.

How similar studies have gone: Other studies have shown that CCTA can provide valuable insights for managing coronary artery disease, indicating a promising approach.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* symptomatic patients with SCP suspected of obstructive CAD.
* referred for CCTA for the assessment of SCP.
* ≥18 years of age.
* signed informed consent.

Exclusion Criteria:

* acute coronary syndromes
* previous CAD or coronary revascularization
* nonsinus rhythm
* cardiomyopathy, valvular disease, congenital heart disease or left cardiac insufficiency because of other reasons

Where it's running

  • Beijing Chaoyang Hospital
    Beijing, Beijing Municipality, China
    Recruiting
  • Hebei Petrochina Central Hospital
    Langfang, Hebei, China
    Recruiting
  • Tianjin Chest Hospital
    Tianjin, Tianjin Municipality, China
    Recruiting
  • Tianjin First Central Hospital
    Tianjin, Tianjin Municipality, China
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.