Using CCTA to improve management of stable chest pain
Improving the Clinical Management of Stable Chest Pain Based on Imaging: a Registry of Computed Tomography Coronary Angiography
Tianjin Chest Hospital · NCT04691037
This study is testing if using a special heart scan called CCTA can help doctors better manage stable chest pain and reduce serious heart problems for patients suspected of having blocked arteries.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 50000 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Tianjin Chest Hospital (other) |
| Locations | 4 sites (Beijing, Beijing Municipality and 3 other locations) |
| Trial ID | NCT04691037 on ClinicalTrials.gov |
What this trial studies
This study aims to enroll patients referred for coronary computed tomography angiography (CCTA) to assess stable chest pain suspected of obstructive coronary artery disease (CAD). Patients will undergo CCTA following established guidelines, and the imaging data will be analyzed using various post-processing software to gather comprehensive anatomical, functional, and histological information. The goal is to determine if CCTA can enhance clinical management, reduce major adverse cardiovascular events (MACE), and improve decision-making regarding further investigations and treatments.
Who should consider this trial
Good fit: Ideal candidates are symptomatic patients aged 18 and older with stable chest pain suspected of obstructive coronary artery disease.
Not a fit: Patients with acute coronary syndromes, previous coronary artery disease or revascularization, and certain heart conditions will not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could lead to better management of stable chest pain and potentially reduce the risk of serious cardiovascular events.
How similar studies have performed: Other studies have shown that CCTA can provide valuable insights for managing coronary artery disease, indicating a promising approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * symptomatic patients with SCP suspected of obstructive CAD. * referred for CCTA for the assessment of SCP. * ≥18 years of age. * signed informed consent. Exclusion Criteria: * acute coronary syndromes * previous CAD or coronary revascularization * nonsinus rhythm * cardiomyopathy, valvular disease, congenital heart disease or left cardiac insufficiency because of other reasons
Where this trial is running
Beijing, Beijing Municipality and 3 other locations
- Beijing Chaoyang Hospital — Beijing, Beijing Municipality, China (RECRUITING)
- Hebei Petrochina Central Hospital — Langfang, Hebei, China (RECRUITING)
- Tianjin Chest Hospital — Tianjin, Tianjin Municipality, China (RECRUITING)
- Tianjin First Central Hospital — Tianjin, Tianjin Municipality, China (RECRUITING)
Study contacts
- Study coordinator: Jia Zhou
- Email: zhoujiawenzhang@126.com
- Phone: +8615522485560
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Coronary Computed Tomography Angiography, Stable Chest Pain, Optimal Medical Therapy, Invasive Coronary Angiography, Revascularization, Major Adverse Cardiovascular Events, Coronary Artery Disease