iPACK plus adductor canal blocks to reduce pain after arthroscopic knee surgery
Official title: Evaluation of the Effectiveness of iPACK (Local Anesthetic Infiltration of the Interspace Between the Popliteal Artery and the Posterior Knee Capsule) and Adductor Canal Blocks on Quality of Recovery in Patients Undergoing Arthroscopic Knee Surgery
Run by Sakarya University · NCT07002580 · Data updated 2026-11-12
This trial will try whether adding an iPACK block to an adductor canal block helps adults have less pain and recover faster after arthroscopic knee surgery.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 50 Years |
| Sex | All |
| Enrollment | 64 (estimated) |
| Sponsor | Sakarya University Academic / other |
| Locations | 1 site (Sakarya) |
| Status | Recruiting |
| Started | July 1, 2025 |
| Main results expected | January 1, 2026 |
| Study ends | April 1, 2026 |
| Registry record updated | February 6, 2026 |
| Trial ID | NCT07002580 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults 18–50 scheduled for arthroscopic knee surgery under spinal anesthesia who are ASA I–III and not on chronic pain medications.
✕Probably not a fit
Patients with coagulopathy, ASA IV–V status, those on chronic pain treatments, or who cannot cooperate or refuse the blocks are unlikely to benefit from this protocol.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
Adults aged 18–50 undergoing arthroscopic knee surgery under spinal anesthesia (ASA I–III) are enrolled and receive standard spinal anesthesia plus peripheral nerve blocks using bupivacaine 0.25%. The intervention arm receives both an adductor canal block and an iPACK block, while the comparison arm receives the adductor canal block alone as part of a multimodal analgesia plan. Key outcomes include postoperative recovery quality, pain scores, opioid consumption, and functional recovery during early follow-up. Patients with coagulopathy, ASA IV–V, chronic pain treatment, inability to cooperate, or who refuse participation are excluded.
Why it matters
Potential benefit: If successful, combining iPACK with an adductor canal block could reduce postoperative pain, lower opioid needs, speed rehabilitation, and shorten hospital stays.
How similar studies have gone: Previous smaller studies and clinical practice reports suggest that combining adductor canal and iPACK blocks can improve postoperative analgesia and reduce opioid use, though larger high-quality trials remain limited.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients aged between 18 and 50 years, * Scheduled for arthroscopic knee surgery under spinal anesthesia due to knee pathology * Patients classified as ASA physical status I-II-III according to the American Society of Anesthesiologists risk classification Exclusion Criteria: * Coagulopathy * ASA IV-V patients * Uncooperable patients * Patients who refuses to participate in study * Patients who takes chronic pain treatments
Where it's running
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Sakarya University Training and Research Hospital
Sakarya, Turkey (Türkiye) Recruiting
Study contacts
- Study coordinator: Oğuzhan Okumuş, M.D.
- Email: dr.oguzhanokumusss@gmail.com
- Phone: +905372093019
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.