Investigation of pre-eclampsia in pregnant women
LimPrOn: Limburg Pre-eclampsia Investigation
This study is testing new ways to monitor pregnant women at high risk for pre-eclampsia to see if it can help catch the condition early and improve treatment.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 2000 (estimated) |
| Ages | 18 Years to 50 Years |
| Sex | Female |
| Sponsor | Hasselt University Academic / other |
| Locations | 8 sites (Bree and 7 other locations) |
| Trial ID | NCT03509272 on ClinicalTrials.gov |
What this trial studies
This study focuses on monitoring pregnant women at high risk for developing pre-eclampsia, a serious condition characterized by high blood pressure and proteinuria. It employs advanced techniques such as NICCOMO and Maternal Venous Doppler Echography, along with bio-electronic impedance analysis, to assess cardiovascular adaptations during pregnancy. The study aims to enhance early detection and treatment through remote monitoring of these patients. A total of 2000 participants will be included from multiple centers.
Who should consider this trial
Good fit: Ideal candidates for this study are pregnant women over 10 weeks gestation, both first-time and experienced mothers.
Not a fit: Patients who are less than 10 weeks pregnant or have congenital malformations of the fetus will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved early detection and management of pre-eclampsia, reducing risks for both mothers and infants.
How similar studies have performed: Other studies have shown promise in using remote monitoring and advanced imaging techniques for managing high-risk pregnancies, indicating potential success for this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * \> 10 weeks of pregnancy, primipara and multipara Exclusion Criteria: * \< 10 weeks of pregnancy and congenital malformations of the fetus
Where this trial is running
Bree and 7 other locations
- Ziekenhuis Maas en Kempen — Bree, Belgium (Recruiting)
- Ziekenhuis Oost-Limburg — Genk, Belgium (Recruiting)
- Jessa Ziekenhuis — Hasselt, Belgium (Recruiting)
- Sint-Fransiscus Ziekenhuis — Heusden-Zolder, Belgium (Recruiting)
- Heilig Hart Ziekenhuis — Mol, Belgium (Recruiting)
- Mariaziekenhuis Oost-Limburg — Overpelt, Belgium (Recruiting)
- Sint-Trudo ziekenhuis — Sint-Truiden, Belgium (Recruiting)
- AZ-vesalius — Tongeren, Belgium (Recruiting)
Study contacts
- Principal investigator: Wilfried Gyselaers, prof. dr. — Hasselt University
- Study coordinator: Dorien Lanssens, drs.
- Email: dorien.lanssens@uhasselt.be
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.