Investigating white matter fibers in the brain during wakefulness and sleep

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to analyze electrophysiological and clinical data from patients aged 14-65 with drug-resistant epilepsy who undergo stereoelectroencephalography (SEEG) to explore the functional characteristics of white matter fibers. By recording brain signals, the study seeks to understand how white matter connectivity changes between wakefulness and sleep. The research focuses on the impact of sleep on brain connectivity and its implications for epilepsy treatment. The findings could provide insights into the neuronal functional states and cortical excitability related to epilepsy.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Drug-resistant focal epilepsy
* Justified SEEG exploration in the context of presurgical assessment of epilepsy
* Subjects will be a part of the epilepsy-monitoring unit for long-term SEEG recordings and analysis
* Written non-opposition to study participation

Exclusion Criteria:

* Pregnant women (Contraindication to SEEG exploration)
* Subjects that experience surgical complications during the implant procedure will be excluded from the study

Where it's running

• Xuanwu Hospital, Beijing
  Beijing, Beijing Municipality, China Recruiting

Study contacts

• Principal investigator: Liankun Ren, MD — Xuanwu Hospital, Beijing
• Study coordinator: Liankun Ren, MD
• Email: renlk2022@outlook.com
• Phone: 13681576621

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.