Investigating the role of the human microbiome in health and disease

Food and Microbiome Longitudinal Investigation (FAMiLI)

Observational NYU Langone Health · NCT03293758

This study is looking to see how the bacteria in our bodies affect health and diseases like cancer and heart problems in people over 40.

Quick facts

Study typeObservational
Enrollment16000 (estimated)
Ages40 Years and up
SexAll
SponsorNYU Langone Health Academic / other
Locations1 site (New York, New York)
Trial IDNCT03293758 on ClinicalTrials.gov

What this trial studies

This observational study aims to enhance the understanding of how the human microbiome influences health and disease, particularly focusing on conditions like cancer and cardiovascular diseases. Participants over the age of 40 will be recruited to contribute to a biorepository that will support future research on human genetics and the microbiome. The study will collect data and samples to analyze the relationship between microbiome composition and various health outcomes. It is conducted by NYU Langone Health in collaboration with the National Cancer Institute.

Who should consider this trial

Good fit: Ideal candidates for this study are individuals over the age of 40 who are not currently using long-term antibiotics and are not pregnant.

Not a fit: Patients who are under 40 years old, pregnant, or have been on long-term antibiotics may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to new insights into the prevention and treatment of cancer and cardiovascular diseases through microbiome modulation.

How similar studies have performed: Other studies have shown promising results in understanding the microbiome's role in health, suggesting that this approach could yield valuable insights.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age \> 40

Exclusion Criteria:

* Use of long term antibiotics.
* Pregnant

Where this trial is running

New York, New York

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions CancerCardiovascular Diseases
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.