Investigating the role of heavy metals in pulmonary arterial hypertension

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to recruit 50 patients diagnosed with pulmonary arterial hypertension (PAH) from the University of Louisville PAH Clinic, categorized into intermediate and high-risk groups, along with 10 matched healthy controls. Participants will undergo evaluations every six months, during which blood and urine samples will be collected to measure levels of 31 different metals, including both heavy and essential metals. The study will analyze the interactions among these metals and their correlation with the severity, duration, and treatment of PAH and right ventricular dysfunction over a 12-month period.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* All patients with the diagnosis of pulmonary hypertension
* Agree to the study protocol
* Healthy volunteers
* Age, gender matched controls

Exclusion Criteria:

* Younger than 18 years
* Refusal to participate

Where it's running

• University of Louisville Health
  Louisville, Kentucky, United States Recruiting

Study contacts

• Study coordinator: Jiapeng Huang, MD, PhD
• Email: jiapeng.huang@louisville.edu
• Phone: 5028528157

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.