Investigating the Role of Fatty Acids in Premature Infants' Eye Development

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study examines the relationship between retinopathy of prematurity (ROP) and the expression of transplacental fatty acid receptors in mothers and their premature infants. It focuses on the role of omega-3 polyunsaturated fatty acids (PUFAs) in retinal vascular development, particularly in infants born before 29 weeks of gestation. By analyzing maternal and umbilical cord blood samples, the study aims to uncover differences in fatty acid levels that may contribute to the risk of ROP. The findings could enhance understanding of how maternal nutrition impacts infant eye health.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Mothers giving birth to premature babies less than 29 weeks of amenorrhea (WA), after obtaining their non-opposition.
2. Mothers giving birth at term between 39 and 41WA+6 days, after obtaining their non-opposition.
3. ≥18 years
4. Mothers not under legal protection

Exclusion Criteria:

1. Mothers giving birth between 29WA and 38WA+6 days
2. Mothers in critical condition.
3. Person not affiliated to national health insurance
4. For full-term mothers: patient presenting or having presented a health condition that affected a previous pregnancy (vascular such as pregnant hypertension, preeclampsia; gestational diabetes; intrauterine growth retardation, maternal infection during pregnancy such as toxoplasmosis, cytomegalovirus, rubella, measles, chickenpox).

Where it's running

• Chu Dijon Bourogne
  Dijon, France Recruiting

Study contacts

• Study coordinator: Catherine CREUZOT-GARCHER
• Email: catherine.creuzot-garcher@chu-dijon.fr
• Phone: 03.80.29.51.73

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.