Clinical trial Recruiting at 2 sites Observational Ages 16 and up

Investigating the role of blood vessel growth in skin diseases

Official title: Role of Angiogenesis in Dermatologic Diseases: A Potential Therapeutic Target

Run by University of California, Irvine · NCT00842283 · Data updated 2026-11-12

This study looks at how the growth of blood vessels affects skin diseases like port wine stains and psoriasis to better understand their causes and treatments.

More Dermatologic Disease trials

Quick facts

Study typeObservational
Ages16 Years and up
SexAll
Enrollment85 (estimated)
SponsorUniversity of California, Irvine
Academic / other
Locations2 sites (Irvine, California and 1 other locations)
StatusRecruiting
StartedNovember 2008
Main results expectedDecember 2028
Study endsDecember 2028
Registry record updatedApril 13, 2026
Trial IDNCT00842283 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are individuals aged 16 years and older who are willing to undergo a skin biopsy.

Probably not a fit

Patients under 16 years of age or those unable to follow instructions may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to explore the role of angiogenesis, or blood vessel growth, in various dermatologic diseases such as port wine stains, hemangiomas, and psoriasis. Researchers will analyze biospecimens, including skin tissue samples, to identify pro-angiogenic factors and their molecular pathways associated with these conditions. The study will utilize discarded skin tissue from surgical procedures and collect de-identified patient data to enhance understanding of angiogenesis in dermatologic diseases. Genetic analysis may also be performed on select specimens to further investigate underlying mechanisms.

Why it matters

Potential benefit: If successful, this research could lead to new therapeutic targets for treating a range of dermatologic diseases.

How similar studies have gone: While the specific approach of this study may be novel, previous research has indicated that targeting angiogenesis can be beneficial in treating certain dermatologic conditions.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* 16 years of age or older.
* willing to have a skin biopsy

Exclusion Criteria:

* under 16 years of age
* unable to carry out instructions

Where it's running

  • Beckman Laser Institute and Medical Clinic
    Irvine, California, United States
    Recruiting
  • Dermatology Clinic at Gavin Herbert Eye Institute
    Irvine, California, United States
    Recruiting

Study contacts

  • Principal investigator: Kristen Kelly, MD — University of California, Irvine
  • Study coordinator: Hanna Kim
  • Email: hhkim3@uci.edu
  • Phone: 949-824-2251

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.