Investigating the role of blood vessel growth in skin diseases
Official title: Role of Angiogenesis in Dermatologic Diseases: A Potential Therapeutic Target
Run by University of California, Irvine · NCT00842283 · Data updated 2026-11-12
This study looks at how the growth of blood vessels affects skin diseases like port wine stains and psoriasis to better understand their causes and treatments.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 16 Years and up |
| Sex | All |
| Enrollment | 85 (estimated) |
| Sponsor | University of California, Irvine Academic / other |
| Locations | 2 sites (Irvine, California and 1 other locations) |
| Status | Recruiting |
| Started | November 2008 |
| Main results expected | December 2028 |
| Study ends | December 2028 |
| Registry record updated | April 13, 2026 |
| Trial ID | NCT00842283 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are individuals aged 16 years and older who are willing to undergo a skin biopsy.
✕Probably not a fit
Patients under 16 years of age or those unable to follow instructions may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to explore the role of angiogenesis, or blood vessel growth, in various dermatologic diseases such as port wine stains, hemangiomas, and psoriasis. Researchers will analyze biospecimens, including skin tissue samples, to identify pro-angiogenic factors and their molecular pathways associated with these conditions. The study will utilize discarded skin tissue from surgical procedures and collect de-identified patient data to enhance understanding of angiogenesis in dermatologic diseases. Genetic analysis may also be performed on select specimens to further investigate underlying mechanisms.
Why it matters
Potential benefit: If successful, this research could lead to new therapeutic targets for treating a range of dermatologic diseases.
How similar studies have gone: While the specific approach of this study may be novel, previous research has indicated that targeting angiogenesis can be beneficial in treating certain dermatologic conditions.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * 16 years of age or older. * willing to have a skin biopsy Exclusion Criteria: * under 16 years of age * unable to carry out instructions
Where it's running
-
Beckman Laser Institute and Medical Clinic
Irvine, California, United States Recruiting -
Dermatology Clinic at Gavin Herbert Eye Institute
Irvine, California, United States Recruiting
Study contacts
- Principal investigator: Kristen Kelly, MD — University of California, Irvine
- Study coordinator: Hanna Kim
- Email: hhkim3@uci.edu
- Phone: 949-824-2251
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.