Investigating the long-term effects of COVID-19 in children

Longterm Influence of Pediatric Long COVID Syndrome on the Neuropsychiatric Function, Social Function, Neuroimage, and Gut Microbiota

Observational National Taiwan University Hospital · NCT05566392

This study is testing the long-term effects of COVID-19 on children's brain health and mental well-being by looking at kids aged 6-18 who had the virus and comparing them to healthy peers.

Quick facts

Study typeObservational
Enrollment500 (estimated)
Ages6 Years to 18 Years
SexAll
SponsorNational Taiwan University Hospital Academic / other
Locations1 site (Taipei)
Trial IDNCT05566392 on ClinicalTrials.gov

What this trial studies

This observational study enrolls pediatric patients aged 6-18 who have been diagnosed with COVID-19 to assess the long-term effects of the virus, specifically focusing on neurological and psychiatric outcomes. Participants will undergo brain MRI and neuropsychiatric evaluations 4-6 months after their COVID-19 diagnosis, with a follow-up evaluation one year later for longitudinal analysis. Healthy age- and gender-matched participants will also be included for comparative purposes.

Who should consider this trial

Good fit: Ideal candidates for this study are children aged 6-18 who have been diagnosed with COVID-19.

Not a fit: Patients with a history of neuropsychiatric disorders or those with devices not allowed for MRI will not benefit from this study.

Why it matters

Potential benefit: If successful, this study could provide valuable insights into the long-term neurological and psychiatric impacts of COVID-19 in children, potentially guiding future treatment and management strategies.

How similar studies have performed: While studies on long COVID are emerging, this specific focus on pediatric long COVID and its neurological effects is relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age 6-18 years old
* Has been diagnosed COVID-19 before

Exclusion Criteria:

* History of neuropsychiatric disorders
* Have some device not allowed for MRI

Where this trial is running

Taipei

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions COVID-19-Associated EncephalitisLong COVIDpediatric neurologypsychiatric evaluationLong COVID syndromemagnetic resonance image
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.