Investigating the link between peri-implantitis and maxillary sinusitis
"Association Between the Treatment of Peri-implantitis and the Resolution of Maxillary Sinusitis: a Case-control Study".
Universitat Internacional de Catalunya · NCT05924711
This study is trying to see if gum disease around dental implants is linked to sinus problems in patients who have had CT scans of their upper jaw.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 40 (estimated) |
| Ages | 18 Years to 80 Years |
| Sex | All |
| Sponsor | Universitat Internacional de Catalunya (other) |
| Locations | 2 sites (Sant Cugat Del Vallès, Barcelona and 1 other locations) |
| Trial ID | NCT05924711 on ClinicalTrials.gov |
What this trial studies
This observational case-control study aims to explore the association between peri-implantitis and maxillary sinusitis, particularly focusing on the effects of peri-implantitis on the thickening of Schneider's membrane. The study will retrospectively analyze demographic and radiographic data from patients with dental implants in the posterior maxillary region who have undergone CT scans. It will also evaluate changes in the maxillary sinus membrane following treatment of peri-implantitis or implant removal. The findings could provide insights into the relationship between these two conditions and their management.
Who should consider this trial
Good fit: Ideal candidates include men and women aged 18-80 with dental implants in the posterior upper jaw and a follow-up of more than 5 years.
Not a fit: Patients with uncontrolled systemic diseases, pregnant or lactating individuals, and those with active periodontal disease may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved treatment strategies for patients suffering from both peri-implantitis and maxillary sinusitis.
How similar studies have performed: While the specific association being studied is not well-documented, similar studies exploring the relationship between dental implants and sinus conditions have shown varying degrees of success.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Men and women between 18-80 years of age * Patients with implants in the posterior sector of the upper jaw * Dental implant carriers with a follow-up of more than 5 years * Patients who have undergone a CT scan for the evaluation of these implants or for other reasons Exclusion Criteria: * Patients with uncontrolled systemic disease * Pregnant or lactating patients * Heavy smokers (HS) * Patients with uncontrolled or active periodontal disease in need of periodontal treatment * Patients with zygomatic or pterygoid implants * Patients taking medications known to modify bone metabolism or who have degenerative bone disease (hyperparathyroidism, osteoporosis), vitamin D, patients who have taken antibiotics, NSAIDs or corticosteroids for more than two weeks in the last 3 months prior to the examination.
Where this trial is running
Sant Cugat Del Vallès, Barcelona and 1 other locations
- Universitat Internacional de Catalunya (UIC) — Sant Cugat Del Vallès, Barcelona, Spain (NOT_YET_RECRUITING)
- Ramon Pons — Barcelona, Spain (RECRUITING)
Study contacts
- Study coordinator: Marta Monzo
- Email: secretariaodonto@uic.es
- Phone: 932 54 18 00
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Peri-Implantitis, Sinusitis, Sinusitis, Acute, Sinusitis, Chronic, Implant Infection, Dental Implant Failure Nos