Investigating the link between HIV infection and male hypogonadism
Official title: Association Between Human Immunodeficiency Virus (HIV) Infection and Male Hypogonadism
Run by National Taiwan University Hospital · NCT04760574 · Data updated 2026-11-12
This study looks at how common low testosterone is in men with HIV compared to men without HIV to see what factors might be linked to it.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 20 Years and up |
| Sex | Men only |
| Enrollment | 1200 (estimated) |
| Sponsor | National Taiwan University Hospital Academic / other |
| Drugs / interventions | chemotherapy, radiation |
| Locations | 1 site (Taipei) |
| Status | Recruiting |
| Started | February 2, 2021 |
| Main results expected | November 2030 |
| Study ends | November 2030 |
| Registry record updated | March 3, 2021 |
| Trial ID | NCT04760574 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include HIV-infected men who have sex with men and HIV non-infected men.
✕Probably not a fit
Patients with a history of testosterone supplement use, certain diseases, or severe health impairments may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study examines the prevalence of hypogonadism among HIV-infected men who have sex with men (MSM) by comparing them to an age-matched group of non-HIV infected MSM. It aims to identify risk factors associated with male hypogonadism, including age, duration of HIV infection, comorbidities, body mass index (BMI), and antiretroviral therapy (ART) use. Additionally, the study will explore the correlation between serum testosterone levels and various health aspects such as sexual function, vitality, exercise capacity, mood, and bone mineral density.
Why it matters
Potential benefit: If successful, this study could enhance understanding of hypogonadism in HIV-infected individuals, leading to better management and treatment options.
How similar studies have gone: While studies on hypogonadism in HIV populations exist, this specific approach focusing on MSM is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * HIV-infected men who have sex with men * HIV non-infected men Exclusion Criteria: * Use of testosterone supplement, anabolic steroid in the past one year. * History of pituitary , adrenal or gonad diseases * History of pituitary surgery or radiation therapy * History of systemic chemotherapy * Active opportunistic infection under treatment * Cancer * Severe hepatic, renal or cardiac impairment
Where it's running
-
National Taiwan University Hospital
Taipei, Taiwan Recruiting
Study contacts
- Study coordinator: Shyang-Rong Shih, Ph.D.
- Email: srshih@ntu.edu.tw
- Phone: +886-2-2312-3456
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.