Investigating the link between HIV infection and male hypogonadism
Association Between Human Immunodeficiency Virus (HIV) Infection and Male Hypogonadism
This study looks at how common low testosterone is in men with HIV compared to men without HIV to see what factors might be linked to it.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 1200 (estimated) |
| Ages | 20 Years and up |
| Sex | Male |
| Sponsor | National Taiwan University Hospital Academic / other |
| Drugs / interventions | chemotherapy, radiation |
| Locations | 1 site (Taipei) |
| Trial ID | NCT04760574 on ClinicalTrials.gov |
What this trial studies
This observational study examines the prevalence of hypogonadism among HIV-infected men who have sex with men (MSM) by comparing them to an age-matched group of non-HIV infected MSM. It aims to identify risk factors associated with male hypogonadism, including age, duration of HIV infection, comorbidities, body mass index (BMI), and antiretroviral therapy (ART) use. Additionally, the study will explore the correlation between serum testosterone levels and various health aspects such as sexual function, vitality, exercise capacity, mood, and bone mineral density.
Who should consider this trial
Good fit: Ideal candidates include HIV-infected men who have sex with men and HIV non-infected men.
Not a fit: Patients with a history of testosterone supplement use, certain diseases, or severe health impairments may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance understanding of hypogonadism in HIV-infected individuals, leading to better management and treatment options.
How similar studies have performed: While studies on hypogonadism in HIV populations exist, this specific approach focusing on MSM is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * HIV-infected men who have sex with men * HIV non-infected men Exclusion Criteria: * Use of testosterone supplement, anabolic steroid in the past one year. * History of pituitary , adrenal or gonad diseases * History of pituitary surgery or radiation therapy * History of systemic chemotherapy * Active opportunistic infection under treatment * Cancer * Severe hepatic, renal or cardiac impairment
Where this trial is running
Taipei
- National Taiwan University Hospital — Taipei, Taiwan (Recruiting)
Study contacts
- Study coordinator: Shyang-Rong Shih, Ph.D.
- Email: srshih@ntu.edu.tw
- Phone: +886-2-2312-3456
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.