Clinical trial Recruiting at 1 site Observational Ages 20 and up Men only

Investigating the link between HIV infection and male hypogonadism

Official title: Association Between Human Immunodeficiency Virus (HIV) Infection and Male Hypogonadism

Run by National Taiwan University Hospital · NCT04760574 · Data updated 2026-11-12

This study looks at how common low testosterone is in men with HIV compared to men without HIV to see what factors might be linked to it.

More Hypogonadism trials

Quick facts

Study typeObservational
Ages20 Years and up
SexMen only
Enrollment1200 (estimated)
SponsorNational Taiwan University Hospital
Academic / other
Drugs / interventionschemotherapy, radiation
Locations1 site (Taipei)
StatusRecruiting
StartedFebruary 2, 2021
Main results expectedNovember 2030
Study endsNovember 2030
Registry record updatedMarch 3, 2021
Trial IDNCT04760574 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates include HIV-infected men who have sex with men and HIV non-infected men.

Probably not a fit

Patients with a history of testosterone supplement use, certain diseases, or severe health impairments may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study examines the prevalence of hypogonadism among HIV-infected men who have sex with men (MSM) by comparing them to an age-matched group of non-HIV infected MSM. It aims to identify risk factors associated with male hypogonadism, including age, duration of HIV infection, comorbidities, body mass index (BMI), and antiretroviral therapy (ART) use. Additionally, the study will explore the correlation between serum testosterone levels and various health aspects such as sexual function, vitality, exercise capacity, mood, and bone mineral density.

Why it matters

Potential benefit: If successful, this study could enhance understanding of hypogonadism in HIV-infected individuals, leading to better management and treatment options.

How similar studies have gone: While studies on hypogonadism in HIV populations exist, this specific approach focusing on MSM is relatively novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* HIV-infected men who have sex with men
* HIV non-infected men

Exclusion Criteria:

* Use of testosterone supplement, anabolic steroid in the past one year.
* History of pituitary , adrenal or gonad diseases
* History of pituitary surgery or radiation therapy
* History of systemic chemotherapy
* Active opportunistic infection under treatment
* Cancer
* Severe hepatic, renal or cardiac impairment

Where it's running

  • National Taiwan University Hospital
    Taipei, Taiwan
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.