Investigating the link between dry eye and eye muscle spasms

Causal Relationship Between Dry Eye and Accommodative Spasm

Observational Far Eastern Memorial Hospital · NCT05120401

This study is trying to see if people with dry eye experience more eye muscle spasms and discomfort when they try to focus on things up close.

Quick facts

Study typeObservational
Enrollment200 (estimated)
Ages20 Years to 99 Years
SexAll
SponsorFar Eastern Memorial Hospital Academic / other
Locations1 site (New Taipei City)
Trial IDNCT05120401 on ClinicalTrials.gov

What this trial studies

This observational study aims to explore the causal relationship between Sicca dry eye patients and the occurrence of accommodative spasm in individuals with presbyopic refractive error. It focuses on understanding how dry eye symptoms, particularly pain and discomfort, may be exacerbated by the effort of accommodation, leading to increased sensitivity and pain responses. The study utilizes the Ocular Surface Disease Index (OSDI) to assess the severity of dry eye symptoms and their impact on patients' quality of life. By examining these relationships, the study seeks to provide insights into the underlying mechanisms of discomfort in dry eye patients.

Who should consider this trial

Good fit: Ideal candidates for this study are adults with diagnosed Sicca dry eye and presbyopic refractive error.

Not a fit: Patients under 20 years old will not benefit from this study as they do not meet the eligibility criteria.

Why it matters

Potential benefit: If successful, this study could lead to better understanding and management of dry eye symptoms, improving the quality of life for affected patients.

How similar studies have performed: While the specific causal relationship being investigated may be novel, previous studies have explored aspects of dry eye and its symptoms, indicating potential for meaningful insights.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

- dry eye

Exclusion Criteria:

* under 20 year old

Where this trial is running

New Taipei City

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Dry Eye
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.