Investigating the link between chemerin levels and diet quality in colorectal cancer patients

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to explore the relationship between serum chemerin levels in individuals diagnosed with colorectal cancer and various inflammatory response parameters, including C-reactive protein and albumin. It will involve 52 colorectal cancer patients and 52 matched healthy individuals, focusing on dietary habits and their impact on inflammation. Participants will undergo body composition analysis and blood tests after fasting to assess their health metrics and dietary intake. The study seeks to compare these findings with those of healthy individuals to better understand the role of diet in cancer-related inflammation.

Why it matters

Who can join: the full rules

Inclusion Criteria:

For patient group

* Between the ages of 18-65,
* At least 3 weeks after surgery
* Individuals newly diagnosed with colorectal cancer by a oncolog (except for Stage IV)

For healthy group

* Between the ages of 18-65,
* Healthy adult individuals without any chronic disease

Exclusion Criteria:

For patient group

* Receiving active radiotherapy or chemotherapy,
* Existing history of metastasis,
* Having a malignant disease other than the diagnosis of colorectal cancer, - History of metabolic syndrome, cardiovascular disease, hepatic disease, chronic kidney disease, major hormonal or hematological disease, pulmonary disease,
* With a history of autoimmune disease, with a history of inflammatory diseases (pancreatitis, chron's, ulcerative colitis, etc.),
* Those who use nonsteroidal anti-inflammatory drugs (NSAIDs),
* Alcoholic and other drug addicts,
* Smokers,
* Those with mental disorders (major depressive disorder, dementia),
* Those who take corticosteroid or hormone therapy,
* Those who have an existing infectious disease, those who receive medical nutrition therapy for any disease

For healthy group

* Individuals aged 18 and under and 65 years and older,
* History of metabolic syndrome, cardiovascular disease, hepatic disease, chronic kidney disease, major hormonal or hematological disease, pulmonary disease,
* With a history of autoimmune disease, with a history of inflammatory diseases (pancreatitis, chron's, ulcerative colitis, etc.),
* Those who use nonsteroidal anti-inflammatory drugs (NSAIDs),
* Pregnant and lactating women,
* Alcoholic and other drug addicts,
* Smokers, those with mental disorders (major depressive disorder, dementia),
* Those taking corticosteroid or hormone therapy,
* Those with existing infectious disease,
* Those receiving medical nutrition therapy for any illness

Where it's running

• Hacettepe University Health Science Faculty, Nutrition and Dietetic Department
  Ankara, Turkey Recruiting
• Ankara Bilkent City Hospital, Oncology Hospital, Medical Oncology Outpatient Clinic
  Ankara, Turkey Recruiting

Study contacts

• Principal investigator: Semra Bakir Angay — Hacettepe University
• Study coordinator: Semra Bakir Angay
• Email: semrabakir@hacettepe.edu.tr
• Phone: +903123051094

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.