Investigating the impact of environmental pollutants on female fertility

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to analyze the effects of various environmental agents, such as bisphenols, ethynylestradiol, and glyphosate, on female fertility. Women undergoing in vitro fertilization (IVF) at the University Hospital of Tours will be recruited to provide blood, urine, and follicular fluid samples, alongside completing a lifestyle questionnaire. The study will assess the relationship between the levels of these pollutants in the samples and the quality of oocytes, as well as the success rates of IVF and pregnancy outcomes. The research seeks to understand how oxidative stress and endocrine disruptors may influence reproductive health.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Woman aged 18 to 43 years old
* First oocyte puncture (IVF rank = 1)

Exclusion Criteria:

* Opposition to data processing
* IVF rank equal or greater than 2
* Egg donation
* Intracytoplasmic Sperm Injection with testicular biopsy
* Intracytoplasmic Sperm Injection with self-preservation straw
* Sperm donation

Where it's running

• Department of Reproductive Medicine and Biology, Univesity Hospital, Tours
  Tours, France Recruiting

Study contacts

• Principal investigator: Fabrice GUERIF, MD-PhD — University Hospital, Tours
• Study coordinator: Fabrice GUERIF, MD-PhD
• Email: fabrice.guerif@univ-tours.fr
• Phone: 02.47.47.84.76

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.