Investigating the heart effects of influenza infection

Influenza and the Heart: An Investigation Into the Acute and Lasting Cardiac Effects of Influenza Infection

University Hospital, Gentofte, Copenhagen · NCT05084846

This study is testing how influenza infection affects the heart in patients who are hospitalized with the flu to better understand any heart problems that might happen during or after their illness.

Quick facts

Study typeObservational
Enrollment300 (estimated)
Ages18 Years and up
SexAll
SponsorUniversity Hospital, Gentofte, Copenhagen (other)
Locations2 sites (Copenhagen and 1 other locations)
Trial IDNCT05084846 on ClinicalTrials.gov

What this trial studies

This study aims to assess the acute and lasting cardiac effects of influenza infection in patients hospitalized with a confirmed diagnosis of influenza. By creating a prospective clinical cohort, the researchers will analyze the cardiovascular complications that may arise during and after the infection. The study will focus on understanding the mechanisms linking influenza to cardiovascular disease, providing valuable insights into patient care and management.

Who should consider this trial

Good fit: Ideal candidates for this study are adults over 18 years old who are hospitalized with a laboratory-confirmed diagnosis of influenza.

Not a fit: Patients who are unable to cooperate, cannot provide informed consent, are pregnant, or are simultaneously positive for COVID-19 may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved understanding and management of cardiovascular complications associated with influenza, ultimately enhancing patient outcomes.

How similar studies have performed: While the specific approach of this study may be novel, previous research has indicated a connection between influenza and cardiovascular complications, suggesting potential for meaningful findings.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* All patients hospitalized at Herlev \& Gentofte University Hospital with a laboratory-confirmed diagnosis of influenza
* \> 18 years of age

Exclusion Criteria:

* Persons not able to cooperate
* Persons unable to understand and sign "informed consent"
* Pregnancy
* Persons simultaneously positive with COVID-19

Where this trial is running

Copenhagen and 1 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Influenza, Cardiovascular Complication

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.