Investigating the effects of vitreopapillary traction on optic disc morphology in glaucoma patients
Vitreopapillary Traction and Optic Disc Morphology in Healthy Subjects, Vitreomacular Traction Patients and Glaucoma Patients
Universitaire Ziekenhuizen KU Leuven · NCT02290795
This study is trying to see how pulling from the vitreous body affects the optic nerve in glaucoma patients to help doctors better diagnose and monitor the disease.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 350 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Universitaire Ziekenhuizen KU Leuven (other) |
| Locations | 1 site (Leuven) |
| Trial ID | NCT02290795 on ClinicalTrials.gov |
What this trial studies
This observational study aims to explore the impact of vitreopapillary traction on the diagnosis and monitoring of glaucoma patients. It focuses on how tractional forces from the vitreous body can influence the optic nerve head and potentially mask disease progression. The study employs advanced imaging techniques, such as OCT and HRT imaging, to assess the morphology of the optic disc and its relationship with vitreous traction. By understanding these dynamics, the research seeks to improve diagnostic accuracy and patient outcomes in glaucoma management.
Who should consider this trial
Good fit: Ideal candidates include adults over 18 years old who are scheduled for glaucoma treatment or have healthy eyes.
Not a fit: Patients with a history of vitrectomy, diabetes, or retinal vessel occlusion may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance the understanding of glaucoma progression and improve diagnostic techniques for better patient management.
How similar studies have performed: Previous studies have indicated that understanding vitreous traction can significantly impact the management of retinal conditions, suggesting potential for success in this area.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * willingness to sign informed consent, aged over 18y, glaucoma/trabeculectomy scheduled/Ocriplasmin scheduled/healthy Exclusion Criteria: * medical history of vitrectomy/diabetes/Retinal Vessel Occlusion
Where this trial is running
Leuven
- University Hospitals Leuven — Leuven, Belgium (RECRUITING)
Study contacts
- Principal investigator: Ingeborg Stalmans, MD PhD — Dpt. Ophthalmology, University Hospitals Leuven, Belgium
- Study coordinator: Ingeborg Stalmans, MD, PhD
- Email: ingeborg.stalmans@uzleuven.be
- Phone: 016 33 23 70
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Posterior Vitreous Detachment, Vitreomacular Traction, Glaucoma, Vitreopapillary Traction, Vitreopapillary traction