Investigating the effects of Synaquell on brain function in youth contact sport athletes

The Effect of Synaquell™ on Objective Measures of Brain Health in Male and Female Youth Contact Sport Athletes

Not applicable Interventional Mayo Clinic · NCT06104670

This study is testing whether a dietary supplement called Synaquell can improve brain health and cognitive function in young ice hockey players.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment40 (estimated)
Ages13 Years to 19 Years
SexAll
SponsorMayo Clinic Academic / other
Locations1 site (Rochester, Minnesota)
Trial IDNCT06104670 on ClinicalTrials.gov

What this trial studies

This clinical trial aims to evaluate the dietary supplement Synaquell in enhancing brain health among youth ice hockey players. The study will randomly assign participants to receive either Synaquell or a placebo throughout an entire season. Researchers will assess brain health using various methods, including EEG measurements, blood and saliva biomarkers, and cognitive tests. The goal is to determine if Synaquell can positively impact cognitive function in athletes engaged in contact sports.

Who should consider this trial

Good fit: Ideal candidates for this study are youth ice hockey players who are medically cleared to participate in contact sports and fluent in English.

Not a fit: Patients with allergies to the ingredients in Synaquell or the placebo, or those with certain medical conditions such as hearing issues or a history of seizures, may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved cognitive health and performance in youth athletes participating in contact sports.

How similar studies have performed: While there have been studies on cognitive supplements, the specific use of Synaquell in this context is novel and has not been extensively tested.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Fluent English Speakers
* Medically cleared to play contact sport

Exclusion Criteria:

* An allergy to the ingredients of Synaquell™ or the placebo (ingredients listed on page
* Clinically documented hearing issues,
* In-ear hearing aid or cochlear implant
* Implanted pacemaker or defibrillator
* Metal or plastic implants in skull
* Lack of verbal fluency in the English language
* History of seizures
* Allergy to rubbing alcohol or EEG gel
* Pregnancy

Where this trial is running

Rochester, Minnesota

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions HealthyIce HockeyCognitive FunctionCognition Brain SupplementContact Sport Athletes
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.