Investigating the effects of physical activity on heart and muscle health in older adults
The Cardio-Sarcopenia Study
This study is testing how different amounts of physical activity can affect heart and muscle health in older adults with a condition that causes both heart and muscle problems.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 200 (estimated) |
| Ages | 21 Years to 99 Years |
| Sex | All |
| Sponsor | National Heart Centre Singapore Academic / other |
| Locations | 1 site (Singapore) |
| Trial ID | NCT05203406 on ClinicalTrials.gov |
What this trial studies
This observational study focuses on older adults with a condition termed cardio-sarcopenia, which involves both cardiovascular and skeletal muscle deterioration. It aims to assess how varying levels of physical activity influence changes in cardiac function, muscle health, and body mass index (BMI) over a period of six to twelve months. Participants will be monitored through self-reported activities and objective measures of aerobic capacity, with data collected on diet, lifestyle, and biomarkers. The study challenges the traditional use of BMI as a health marker in older adults, potentially leading to new preventative strategies against cardiovascular aging.
Who should consider this trial
Good fit: Ideal candidates for this study are older adults aged 21 and above who exhibit signs of cardio-sarcopenia.
Not a fit: Patients who are unable to provide informed consent or do not meet the age criteria may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide insights into effective physical activity interventions that improve heart and muscle health in older adults.
How similar studies have performed: While the concept of cardio-sarcopenia is relatively novel, previous studies have indicated the importance of physical activity in mitigating age-related cardiovascular and muscle decline.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * \>=21 years of age Exclusion Criteria: * Unable to provide written informed consent to participate in the study.
Where this trial is running
Singapore
- National Heart Centre Singapore — Singapore, Singapore (Recruiting)
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.