Investigating the effects of occlusal adjustment on orofacial pain
An Follow-up Study of Occlusal Adjustment for Orofacial Pain
This study is testing if adjusting how your teeth fit together can help reduce orofacial pain, like trigeminal neuralgia, by looking at muscle activity and pain levels before and after treatment.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 30 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Air Force Military Medical University, China Academic / other |
| Drugs / interventions | radiation |
| Locations | 1 site (Xi'an, Shaanxi) |
| Trial ID | NCT02856906 on ClinicalTrials.gov |
What this trial studies
This study aims to explore the relationship between dental occlusion and orofacial pain, specifically focusing on trigeminal neuralgia. Researchers will utilize a T-scan analysis system to assess occlusal contact relationships and employ electromyography to measure muscle activity in the masseter and anterior temporalis muscles before and after occlusal adjustment treatment. The study will also track pain frequency and intensity using visual analogue scales and other assessments over a follow-up period of 24 weeks.
Who should consider this trial
Good fit: Ideal candidates include individuals experiencing orofacial pain that has not responded to medications or surgical interventions, particularly those with trigeminal neuralgia.
Not a fit: Patients with orofacial pain that is not related to dental occlusion or those who have not experienced relief from pain through other means may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide a non-invasive treatment option for patients suffering from orofacial pain that is resistant to conventional therapies.
How similar studies have performed: While there is limited data on the specific approach of occlusal adjustment for orofacial pain, similar studies have shown promise in addressing dental occlusion-related pain.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * The patients claim orofacial pain. The pain has been treated but not relieved by medication, surgery, root canal therapy, even teeth extracting, or the pain relieve effect went down for a period. The patients also match the following item 1 or 2: * Item 1: disorder characterized by recurrent unilateral brief electric shock-like pains, abrupt in onset and termination, limited to the distribution of one or more divisions of the trigeminal nerve and triggered by innocuous stimuli. It may develop without apparent cause or be a result of another diagnosed disorder. There may or may not be, additionally, persistent background facial pain of moderate intensity.They fulfilled criteria A-E * At least three attacks of unilateral facial pain fulfilling criteria B and C * Occurring in one or more divisions of the trigeminal nerve, with no radiation beyond the trigeminal distribution * Pain has at least three of the following four characteristics: * recurring in paroxysmal attacks lasting from a fraction of a second to 2 minutes. * severe intensity. * electric shock-like, shooting, stabbing or sharp in quality. * precipitated by innocuous stimuli to the affected side of the face. * No clinically evident neurological deficit * Not better accounted for by another the International Classification of Headache Disorders 3rd edition diagnosis. * Item 2 Persistent facial and/or oral pain, with varying presentations but recurring daily for more than 2 hours per day over more than 3 months, in the absence of clinical neurological deficit.They fulfilled criteria A-E * Facial and/or oral pain fulfilling criteria B and C * Recurring daily for \>2 hours per day for \>3 months * Pain has both of the following characteristics: 1. poorly localized, and not following the distribution of a peripheral nerve 2. Dull, aching or nagging quality * Clinical neurological examination is normal * A dental cause has been excluded by appropriate investigations * Not better accounted for by another the International Classification of Headache Disorders 3rd edition diagnosis Exclusion Criteria: * Head and facial trauma; orofacial and/or intracranial space occupying lesion indicated by craniofacial CT ; pain caused by sinusitis and acute pulpitis, periapical periodontitis and periodontitis disease; no occlusal abnormalities and occlusion treatment indications through a series of occlusal examination; children (younger than 18 years old) and pregnant women.
Where this trial is running
Xi'an, Shaanxi
- State Key Laboratory of Military Stomatology, Department of Oral Anatomy and Physiology and TMD，School of Stomatology, The Fourth Military Medical University, Xi 'an, China. — Xi'an, Shaanxi, China (Recruiting)
Study contacts
- Study coordinator: Shaoxiong Guo, M.D
- Email: xiongshao1989@163.com
- Phone: 8615902969892
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.