Investigating the effects of laparotomy and pain management on diaphragm function

The Impact of Laparotomy and Analgesia Methods on Postoperative Diaphragm Muscle Contraction in Major Abdominal Surgeries.

Observational Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization · NCT06403540

This study is trying to see how different pain relief methods after major abdominal surgery affect the diaphragm's ability to function in patients.

Quick facts

Study typeObservational
Enrollment90 (estimated)
Ages18 Years and up
SexAll
SponsorProf. Dr. Cemil Tascıoglu Education and Research Hospital Organization Academic / other
Locations1 site (Istanbul)
Trial IDNCT06403540 on ClinicalTrials.gov

What this trial studies

This observational study aims to explore how laparotomy and different analgesia methods impact diaphragm function in patients undergoing major abdominal surgeries. The researchers will measure diaphragm muscle thickness using ultrasonography before and after surgery to assess the effects of various pain management techniques, including intravenous drugs, epidural catheters, and abdominal plane blocks. By analyzing diaphragm contraction during different breathing phases, the study seeks to provide insights into postoperative respiratory function.

Who should consider this trial

Good fit: Ideal candidates for this study are adults over 18 years old who are scheduled for major abdominal surgeries.

Not a fit: Patients with a body mass index over 35 kg/m2, communication issues, or those with certain chronic respiratory or neuromuscular disorders may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved pain management strategies that enhance respiratory function after major abdominal surgeries.

How similar studies have performed: While the specific approach of this study may be novel, similar studies have indicated that effective pain management can significantly improve postoperative respiratory outcomes.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* over 18 years,
* major abdominal surgery cases

Exclusion Criteria:

* body mass index (BMI) \>35 kg/m2
* illiteracy,
* communication issues,
* neuromuscular disorders,
* Advanced chronic respiratory disease,
* Previous abdominal or thoracic surgery

Where this trial is running

Istanbul

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Colorectal NeoplasmsGastrectomy
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.