Investigating the effects of dietary salicylates on preeclampsia
Official title: Nutritional Sources of Salicylates and Disorders of Placental Angiogenesis in Preeclampsia
Run by Poznan University of Life Sciences · NCT06239363 · Data updated 2026-11-12
This study is trying to see if the amount of salicylates in food can affect the risk of developing preeclampsia in pregnant women.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years to 45 Years |
| Sex | Women only |
| Enrollment | 500 (estimated) |
| Sponsor | Poznan University of Life Sciences Academic / other |
| Locations | 1 site (Poznan) |
| Status | Recruiting |
| Started | January 8, 2024 |
| Main results expected | September 28, 2027 |
| Study ends | September 30, 2028 |
| Registry record updated | April 1, 2026 |
| Trial ID | NCT06239363 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are pregnant women aged 18-45, both healthy and those diagnosed with preeclampsia, who can provide informed consent.
✕Probably not a fit
Patients with detectable fetal defects, chronic hypertension, or other significant medical conditions may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to explore the relationship between maternal dietary intake of salicylates and the risk of developing preeclampsia, a serious pregnancy complication. It will compare the effects of naturally occurring salicylates found in food with those of low-dose aspirin on placental angiogenesis. The study will involve approximately 500 pregnant women, both healthy and those diagnosed with preeclampsia, aged 18-45 years. Participants will provide information about their daily food intake to assess the potential preventive effects of salicylates on preeclampsia development.
Why it matters
Potential benefit: If successful, this study could provide insights into dietary modifications that may help reduce the risk of preeclampsia in pregnant women.
How similar studies have gone: While the influence of salicylates on preeclampsia is a relatively novel area of investigation, previous studies have shown that low-dose aspirin can reduce the risk of preeclampsia, suggesting potential for success in this approach.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * age 18-45 years * healthy women with no previous adverse medical history and women with diagnosed preeclampsia * singleton pregnancy * people who have the full ability to give informed consent. Exclusion Criteria: * pregnancies with detectable fetal defects, chromosomal abnormalities, genetic syndromes * infections * history of chronic hypertension, metabolic disorder before or during pregnancy, or the presence of high-risk factors such as heart diseases, diabetes, and renal diseases.
Where it's running
-
Poznan University of Life Sciences
Poznan, Poland Recruiting
Study contacts
- Study coordinator: Joanna Suliburska, Professor
- Email: joanna.suliburska@up.poznan.pl
- Phone: +48 61 8487260
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.