Investigating the effects of anti-thrombosis on brain microbleeds in stroke patients

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This prospective cohort study aims to explore the relationship between antithrombotic therapy and the occurrence of cerebral microbleeds (CMBs) in patients who have experienced an ischemic stroke. It will assess whether such therapy increases the risk of new CMBs and whether these changes correlate with a higher incidence of intracranial hemorrhage. The study will utilize advanced imaging techniques to gather evidence that could inform personalized antithrombotic treatment strategies for these patients. By focusing on a specific patient population, the research seeks to clarify the risks associated with antithrombotic medications in the context of ischemic stroke.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Patient age ≥18 years;
2. Acute ischemic stroke patient confirmed by imaging;
3. Time of onset: within 3 months;
4. Baseline SWI sequence is completed before starting the secondary prevention of ischemic stroke;
5. Baseline SWI sequence must have at least one CMB ;
6. NIHSS≤10

Exclusion Criteria:

1. MRI contraindication;
2. Hemorrhagic transformation after acute Ischemic stroke;
3. Contraindication for antiplatelet or anticoagulation therapy;
4. Severe head trauma or intracranial hemorrhage occurred in the past six months;
5. obvious coagulopathy;
6. Other intracranial lesions associated with (such as tumor, cerebral vascular malformation);
7. other unqualified patients judged by the investigator

Where it's running

• General Hospital of ShenYang Military Region
  Shenyang, China Recruiting

Study contacts

• Study coordinator: chen huisheng, doctor
• Email: chszh@aliyun.com
• Phone: 86-24-28897511

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.