Investigating sleep and cognition in patients with focal epilepsy
Sleep Architecture & Cognition in Focal Epilepsy
This study is testing how sleep patterns affect thinking skills in people with focal epilepsy to see if new treatments can help improve both sleep and cognition.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 40 (estimated) |
| Ages | 18 Years to 40 Years |
| Sex | All |
| Sponsor | University of California, Davis Academic / other |
| Locations | 1 site (Sacramento, California) |
| Trial ID | NCT05794295 on ClinicalTrials.gov |
What this trial studies
This study examines the relationship between sleep architecture and cognitive deficits in patients with focal epilepsy (FE) compared to healthy controls. Participants will wear an actigraph and a home sleep study device, followed by two nights of testing at California Sleep Solutions, where they will undergo EEG monitoring and cognitive assessments. The study aims to characterize sleep patterns in FE and evaluate the effects of acoustic and electrical stimulation on sleep and cognitive processing. The ultimate goal is to develop tailored interventions to improve sleep and cognition in individuals with epilepsy.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18-40 with a diagnosis of focal epilepsy who can cooperate with study protocols.
Not a fit: Patients with significant neurological disorders affecting cognition or those currently using medications that impact cognitive function may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved cognitive functioning and sleep quality for patients with focal epilepsy.
How similar studies have performed: While the specific approach of this study is novel, previous studies have indicated potential benefits of sleep interventions in epilepsy management.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age 18 - 40 years of age * Focal Epilepsy * Capacity to fully cooperate and follow directions * no other significant neurological disorders which could affect cognition Exclusion Criteria: * Current use of any medications that can significantly affect cognition * No severe sleep apnea
Where this trial is running
Sacramento, California
- UC Davis — Sacramento, California, United States (Recruiting)
Study contacts
- Study coordinator: Temitayo Oyegbile-Chidi, MD
- Email: oyegbilechidi@health.ucdavis.edu
- Phone: 916-318-3111
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.