Investigating risk factors for kidney injury in lung surgery patients
Risk Factors for Acute Kidney Injury in Patients Undergoing Video-Assisted Thoracoscopic Surgery for Pulmonary Resection: A Prospective Observational Study
This study is trying to find out what factors might lead to kidney problems in patients having lung surgery for cancer.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 100 (estimated) |
| Ages | 18 Years to 65 Years |
| Sex | All |
| Sponsor | Atatürk Chest Diseases and Chest Surgery Training and Research Hospital Academic / other |
| Locations | 1 site (Ankara, Keçiören) |
| Trial ID | NCT06341933 on ClinicalTrials.gov |
What this trial studies
This observational study aims to identify factors that may contribute to Acute Kidney Injury (AKI) in patients undergoing Video Assisted Thoracoscopic Surgery (VATS) for lung cancer. It will analyze demographic data, laboratory parameters, perioperative fluid management, and hemodynamics in patients who have provided informed consent. Participants will be categorized based on specific changes in kidney function indicators, allowing for a comparison of risk factors between groups. The research will be conducted at SBÜ Ankara Atatürk Sanatorium Training and Research Hospital.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18 to 65 with ASA physical status 1-3 undergoing elective VATS for lung malignancy.
Not a fit: Patients with significant renal impairment or those with certain comorbidities such as congestive heart failure may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved strategies for preventing AKI in patients undergoing lung surgery.
How similar studies have performed: While similar studies have explored AKI in surgical settings, this specific focus on VATS and its associated risk factors is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Over 18 years of age, under 65 years of age, * American Society of Anesthesiologists (ASA) physical status 1-3, * Data of patients who will undergo wedge resection, segmentectomy or lobectomy with elective VATS due to lung malignancy will be examined prospectively. Exclusion Criteria: * Patients with a body mass index (BMI) less than 18.5kg/m2 or greater than 35 kg/m2, * Those with impaired renal function (the upper limit of the creatinine reference range is more than 50%; 1.3 mg/dL for men and 1.1 mg/dL for women), * A radiological examination was performed using radiocontrast material in the preoperative period, * Clinically and radiologically diagnosed with congestive heart failure and treatment has been started, * Having a history of pulmonary edema, * Those who have used steroids and non-steroidal anti-inflammatory drugs for a long time (exceeding 30 days), * Intubated to intensive care unit, * In need of massive peroperative blood transfusion, * Patients with deficiencies in the parameters examined will be excluded from the study.
Where this trial is running
Ankara, Keçiören
- Ankara Atatürk Sanatorium Training and Research Hospital — Ankara, Keçiören, Turkey (Türkiye) (Recruiting)
Study contacts
- Principal investigator: Ali ALAGÖZ, professor — Ankara Ataturk Sanatorium Training and Research Hospital
- Study coordinator: Ali ALAGÖZ, professor
- Email: mdalagoz@gmail.com
- Phone: 5079193765
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.