Investigating rehabilitation after knee replacement surgery

Feasibility of a Randomized Trial Comparing Exercise-based Rehabilitation With Non-exercise-based Recovery After Total Knee Arthroplasty; DRAW-TKA Hybrid 1 Feasibility Trial

Not applicable Interventional Copenhagen University Hospital, Hvidovre · NCT05935020

This study is testing a new recovery program for people who have had knee replacement surgery to see if it helps them heal better and if it's practical to do on a larger scale.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment24 (estimated)
Ages18 Years and up
SexAll
SponsorCopenhagen University Hospital, Hvidovre Academic / other
Locations2 sites (Hvidovre and 1 other locations)
Trial IDNCT05935020 on ClinicalTrials.gov

What this trial studies

This feasibility trial aims to assess the practicality of an intervention for patients recovering from total knee replacement due to osteoarthritis. It focuses on understanding patient recruitment, retention, and the safety of the non-exercise intervention. The study will evaluate participants' willingness to engage in the trial and the effectiveness of trial procedures over a 12-week follow-up period. The findings will inform whether a larger-scale trial is feasible based on various feasibility criteria.

Who should consider this trial

Good fit: Ideal candidates are adults over 18 years old who are referred for total knee arthroplasty due to osteoarthritis.

Not a fit: Patients with severe surgical complications or those unable to understand the study materials due to language barriers may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could improve rehabilitation strategies for patients recovering from knee replacement surgery.

How similar studies have performed: While this approach is focused on feasibility, similar studies have shown promise in improving rehabilitation outcomes for knee surgery patients.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Over 18 years of age
* Residing in one of five collaboration municipalities
* Referral to primary total knee arthroplasty for osteoarthritis

Exclusion Criteria:

* Insufficient danish skills (read/write/speak) to understand questionnaires and outcomes
* Inability to provide informed consent
* Severe surgical sequelae (i.e. requiring revision surgery, joint mobilization under anaestesia, or joint infection)

Where this trial is running

Hvidovre and 1 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Osteoarthritis, KneeTotal Knee ReplacementExercise-based Rehabilitation
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.