Investigating Pain Relief from Pregabalin, Duloxetine, and Tramadol in Neuropathic Pain
Study of Analgesic Action of Pregabalin, Duloxetine and Tramadol in Patients With Different Neuropathic Pain Phenotypes. Clinical Study
This study is testing whether the pain medications Pregabalin, Duloxetine, and Tramadol can help people with different types of nerve pain feel better.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 100 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Aristotle University Of Thessaloniki Academic / other |
| Locations | 1 site (Thessaloniki) |
| Trial ID | NCT06252116 on ClinicalTrials.gov |
What this trial studies
This study aims to evaluate the effectiveness of analgesics, specifically Pregabalin, Duloxetine, and Tramadol, in patients suffering from various phenotypes of neuropathic pain. It recognizes that neuropathic pain can manifest differently among individuals, even with similar underlying conditions, and seeks to understand how these medications perform across these diverse presentations. The study will utilize questionnaires and laboratory assessments to classify pain phenotypes and measure treatment outcomes. By focusing on the specific characteristics of neuropathic pain, the study hopes to provide insights into more effective pain management strategies.
Who should consider this trial
Good fit: Ideal candidates for this study are adults experiencing neuropathic pain without any contraindicating health conditions.
Not a fit: Patients with cancer pain, those under 18 years old, or individuals currently taking the studied medications may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to more tailored and effective pain management options for patients with neuropathic pain.
How similar studies have performed: Previous studies have shown varying degrees of success with similar analgesic approaches, but this study focuses specifically on the phenotypic differences in neuropathic pain, making it a novel investigation.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * neuropathic pain Exclusion Criteria: * under 18 years old * cancer pain * patients receiving pregabalin, duloxetine, tramadol * drug or alcohol abuse * psychiatric decease * renal failure, heart failure, liver failure, thrombocytopenia, closed-angle glaucoma
Where this trial is running
Thessaloniki
- AHEPA University General of Thessaloniki, Chronic Pain Unit — Thessaloniki, Greece (Recruiting)
Study contacts
- Study coordinator: Ioannis Dalakakis, MD, MSc
- Email: idalakakis@gmail.com
- Phone: +306948536554
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.