Investigating outcomes after treatment for pulmonary embolism
Clinical Outcomes After Acute Pulmonary Embolism - The Bern Acute Pulmonary Embolism Registry
This study looks at how well different treatments for pulmonary embolism work and how safe they are for patients, using data from a team of experts.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 800 (estimated) |
| Sex | All |
| Sponsor | Insel Gruppe AG, University Hospital Bern Academic / other |
| Locations | 2 sites (Bern, Canton of Bern and 1 other locations) |
| Trial ID | NCT04355975 on ClinicalTrials.gov |
What this trial studies
This observational study aims to evaluate the safety and effectiveness of treatments for pulmonary embolism (PE) as determined by a multi-disciplinary pulmonary embolism response team (PERT). It will collect both retrospective and prospective data on treatment outcomes, including advanced modalities like systemic thrombolysis and surgical embolectomy. The study will analyze health-related outcomes of patients treated for acute and chronic PE, focusing on optimizing treatment protocols and institutional algorithms. Data will be gathered from patients treated between 2001 and 2020, with ongoing prospective data collection starting in May 2020.
Who should consider this trial
Good fit: Ideal candidates include patients diagnosed with pulmonary embolism who meet the treatment criteria set by the PERT.
Not a fit: Patients with a high likelihood of not adhering to follow-up requirements may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance treatment strategies for pulmonary embolism, leading to improved patient outcomes.
How similar studies have performed: Other studies have shown success in optimizing treatment protocols for pulmonary embolism, indicating that this approach is supported by prior research.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Consecutive patients with pulmonary embolism matching the criteria for treatment according to the decision of the PERT. * Written informed consent Exclusion Criteria: * High probability of non-adherence to the follow up requirements
Where this trial is running
Bern, Canton of Bern and 1 other locations
- University Hospital Bern - Inselspital — Bern, Canton of Bern, Switzerland (Recruiting)
- University Hospital Bern — Bern, Switzerland (Recruiting)
Study contacts
- Principal investigator: Stefan Stortecky, MD — Department of Cardiology, Bern University Hospital, University of Bern, Switzerland
- Study coordinator: Stefan Stortecky, MD
- Email: stefan.stortecky@insel.ch
- Phone: +41 31 632 21 11
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.