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Clinical trial Recruiting at 1 site Interventional Ages 18 to 80

Investigating opioid prescriptions after hip arthroscopy

Official title: Randomized Control Trial Evaluating Postoperative Opioid Demands Following Hip Arthroscopy

Run by Rush University Medical Center · NCT04094701 · Data updated 2026-11-12

This study is testing if giving fewer pain pills after hip surgery can still help patients manage their pain while using less medication.

Quick facts

Study typeInterventional
Ages18 Years to 80 Years
SexAll
Enrollment170 (estimated)
SponsorRush University Medical Center
Academic / other
Locations1 site (Chicago, Illinois)
StatusRecruiting
StartedOctober 21, 2020
Main results expectedNovember 2027
Study endsMarch 2028
Registry record updatedAugust 13, 2026
Trial IDNCT04094701 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are adults aged 18-80 who are opioid naive and undergoing primary hip arthroscopy.

Probably not a fit

Patients with a history of opioid use, chronic pain conditions, or other significant health issues may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial is a prospective, single-blinded, randomized controlled trial that examines the impact of different opioid prescription amounts following primary hip arthroscopy. Participants will be randomly assigned to receive either a reduced opioid regimen of 5 Norco pills along with gabapentin and Tylenol or the standard regimen of 30 Norco pills. The study will track postoperative pain scores, total morphine equivalents used, and patient-reported outcomes over a 12-month follow-up period. The goal is to determine if a reduced opioid prescription can effectively manage pain while minimizing opioid use.

Why it matters

Potential benefit: If successful, this study could lead to safer postoperative pain management strategies that reduce reliance on opioids.

How similar studies have gone: Other studies have shown promising results with reduced opioid prescribing strategies, indicating potential for success in this approach.

Who can join: the full rules

Show full inclusion / exclusion criteria 
Inclusion Criteria:

* Adult patients age 18-80 years
* English speaking
* Opioid naive patient (defined as not taking opioid pills within 6 weeks prior to surgery), confirmed by checking the Illinois Prescription monitoring program
* Primary hip arthroscopy
* Written and informed consent for study participation

Exclusion Criteria:

* Minors (\<18 years of age)
* Opioid tolerant patients
* Revision surgery
* Prior infections of the operative joint
* History of active malignancy within the past 5 years
* Chronic pain conditions including low back pain, chronic pain syndrome, fibromyalgia
* History of alcohol or other substance use disorder
* Other disease states including rheumatologic conditions, diabetes mellitus, hypo/hyperthyroidism, depression, anxiety
* Grade IV chondral defects

Where it's running

  • Rush University Medical Center
    Chicago, Illinois, United States     Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
View on ClinicalTrials.gov ↗ Find more trials like this →
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Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.