Investigating new biomarkers in patients with heart attacks
Clinical, Laboratory and Echocardiographic Assessment of Biomarkers in Patients With Acute Myocardial Infarction
Aristotle University Of Thessaloniki · NCT05791916
This study is testing new blood markers and heart scans in people having their first heart attack to see how they can help doctors understand and treat the condition better.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 500 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Aristotle University Of Thessaloniki (other) |
| Locations | 2 sites (Thessaloníki, Central Macedonia and 1 other locations) |
| Trial ID | NCT05791916 on ClinicalTrials.gov |
What this trial studies
This observational study aims to evaluate the clinical value of novel biomarkers and echocardiographic indices in patients experiencing their first acute myocardial infarction (AMI). It will involve a prospective registry of eligible adult patients admitted to the Department of Cardiology at AHEPA University General Hospital in Thessaloniki, Greece. Participants will undergo comprehensive medical interviews and laboratory assessments, alongside transthoracic echocardiographic evaluations to analyze cardiac function and prognostic implications of the findings.
Who should consider this trial
Good fit: Ideal candidates include adults over 18 years old who are acutely admitted with their first acute myocardial infarction and have no prior history of coronary artery disease.
Not a fit: Patients under 18 years old, those with a history of coronary artery disease, or those unable to provide informed consent may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved prognostic tools for better management of patients with acute myocardial infarction.
How similar studies have performed: While this approach is novel in its specific focus on new biomarkers and echocardiographic indices in AMI, similar studies have shown promise in identifying prognostic factors in cardiovascular diseases.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Patients older than 18 years 2. Patients acutely admitted at the Department of Cardiology of AHEPA University General Hospital, Thessaloniki, Greece with Acute Myocardial Infarction, as those are defined by the Fourth Universal Definition of Myocardial Infarction. 3. Patients without known history of coronary artery disease Exclusion Criteria: 1. Patients \< 18 years old at time of coronary angiography 2. Patients with a previous history of coronary artery disease and/or prior revascularization 3. Inability or refusal to provide informed consent 4. Subject is pregnant and/or breastfeeding or intends to become pregnant during the study
Where this trial is running
Thessaloníki, Central Macedonia and 1 other locations
- AHEPA University Hospital, Thessaloniki, Greece — Thessaloníki, Central Macedonia, Greece (RECRUITING)
- AHEPA University Hospital, Thessaloniki, Greece — Thessaloníki, Central Macedonia, Greece (RECRUITING)
Study contacts
- Principal investigator: Vasileios Kamperidis, MD, MSc, PhD — School of Medicine, Aristotle University of Thessaloniki
- Study coordinator: Christos Savopoulos, MD, PhD
- Email: chrisavopoulos@gmail.com
- Phone: 6944569749
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Cardiovascular Diseases, Myocardial Infarction, Acute Coronary Syndrome, Biochemical Dysfunction, Echocardiography, Myocardial Work, Biomarkers