Investigating muscle function in children with obstetric brachial plexus palsy
Study of the Biological Function of Muscle Satellite Cells From Patients With Obstetric Brachial Plexus Palsy Satellite Cell Obstetrical PlExus (SCOPE)
This study is testing how obstetric brachial plexus palsy affects shoulder muscles in children to find better ways to treat shoulder stiffness.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 8 (estimated) |
| Ages | 2 Years to 15 Years |
| Sex | All |
| Sponsor | University Hospital, Montpellier Academic / other |
| Locations | 1 site (Montpellier) |
| Trial ID | NCT05403034 on ClinicalTrials.gov |
What this trial studies
This study aims to explore the effects of obstetric brachial plexus paralysis on the shoulder's rotator muscles in children. It hypothesizes that shoulder stiffness results from an imbalance between affected and less affected muscles. By conducting muscle biopsies, the researchers will assess the regenerative capabilities of these muscles and develop a cellular model to test new therapeutic approaches. The findings could lead to better understanding and management of shoulder stiffness in affected children.
Who should consider this trial
Good fit: Ideal candidates for this study are children diagnosed with obstetric brachial plexus palsy who are scheduled for shoulder surgery.
Not a fit: Patients with other neurological disorders or post-traumatic shoulder stiffness may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could improve treatment strategies for children with obstetric brachial plexus palsy, potentially enhancing their shoulder mobility and overall quality of life.
How similar studies have performed: While this approach is innovative, similar studies have not been widely reported, indicating a novel exploration in this area.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * OBPP children with a planned shoulder surgery (arthrolysis and/or muscle transfer). Exclusion Criteria: * other neurological disorders, post-traumatic shoulder stiffness
Where this trial is running
Montpellier
- Chu Montpellier — Montpellier, France (Recruiting)
Study contacts
- Principal investigator: Marion DELPONT, Dr — University Hospital, Montpellier
- Study coordinator: Marion DELPONT, Dr
- Email: m-delpont@chu-montpellier.fr
- Phone: +33 467335035
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.