Investigating muscle and tissue changes in ICU patients using ultrasound and impedance
Cross-sectional Study on the Variation of Muscle Thickness and Subcutaneous Tissues by Ultrasound and Bioelectrical Impedance in Association with the Fluid Balance of Patients in Intensive Care
This study looks at how changes in muscle and tissue in ICU patients relate to fluid levels in their bodies to see if managing fluid can help improve their recovery.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 40 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Laboratory of Movement, Condorcet, Tournai, Belgium Academic / other |
| Locations | 2 sites (Boussu, Hainaut and 1 other locations) |
| Trial ID | NCT06697470 on ClinicalTrials.gov |
What this trial studies
This observational study examines the relationship between muscle thickness and subcutaneous tissue variations, measured by ultrasound, and fluid balance assessed through bioelectrical impedance analysis (BIA) in critically ill patients in the ICU. The study aims to understand how fluid overload affects muscle mass measurements during the early days of ICU admission, as muscle wasting and edema are common complications in this population. By correlating daily fluid balance with muscle and tissue assessments, the research seeks to provide insights that could guide treatment interventions for improving patient outcomes.
Who should consider this trial
Good fit: Ideal candidates for this study are adults over 18 years old who are admitted to the ICU and can provide informed consent.
Not a fit: Patients with a short expected ICU stay, skin conditions affecting measurements, or those who have made a decision to withdraw therapy will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved monitoring and management of muscle wasting and fluid balance in critically ill patients, enhancing recovery and functional outcomes.
How similar studies have performed: While the use of ultrasound and BIA in assessing muscle and fluid balance is established, this specific correlation in critically ill patients is novel and has not been extensively tested.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adults aged over 18 years. * Patients present and admitted to the ICU at Epicura Hornu Hospital between October 14, 2024, and November 15, 2024 (to be updated). * Informed consent to participate in the study has been signed by the patient or their legal representative. Exclusion Criteria : * Patients in post-operative or other surveillance with an expected ICU stay of less than 48 hours. * Patients for whom a decision to withdraw therapy has been made prior to inclusion. * Presence of skin conditions (e.g., wounds or ulcers) that hinder ultrasound measurements or the application of skin electrodes. * Pregnancy. * Presence of an implanted pacemaker or defibrillator.
Where this trial is running
Boussu, Hainaut and 1 other locations
- Epicura site Hornu — Boussu, Hainaut, Belgium (Recruiting)
- Epicura site Hornu — Boussu, Belgium (Recruiting)
Study contacts
- Study coordinator: Cheryl E HICKMANN, PhD
- Email: c.hickmannopazo@condorcet.be
- Phone: +32488381526
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.