Investigating molecular profiles in colorectal cancer progression
Molecular Pathology of Colorectal Cancer: Investigating the Role of Novel Molecular Profiles, microRNA's, and Their Targets in Colorectal Cancer
University of Southampton · NCT03309722
This study is trying to find new biological markers in people with colorectal cancer to better understand how the disease progresses.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 1000 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | University of Southampton (other) |
| Locations | 1 site (Southampton) |
| Trial ID | NCT03309722 on ClinicalTrials.gov |
What this trial studies
This observational cohort study aims to evaluate and identify novel biomarkers associated with colorectal cancer progression. Patients with colorectal cancer will be prospectively recruited for biomarker evaluation, focusing on the role of microRNAs and their targets. The study will take place at a single center, the University Hospital Southampton, and will involve detailed molecular pathology assessments to enhance understanding of the disease.
Who should consider this trial
Good fit: Ideal candidates for this study are individuals diagnosed with colorectal cancer.
Not a fit: Patients with hereditary colorectal cancer or tumors exhibiting extensive necrosis may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to the discovery of new biomarkers that improve diagnosis and treatment strategies for colorectal cancer patients.
How similar studies have performed: Other studies investigating molecular profiles and biomarkers in colorectal cancer have shown promise, suggesting potential for success in this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * colorectal cancer Exclusion Criteria: * hereditary CRC; tumours with extensive necrosis
Where this trial is running
Southampton
- University Hospital Southampton — Southampton, United Kingdom (RECRUITING)
Study contacts
- Study coordinator: Alex Mirnezami, MD PhD
- Email: ahm@soton.ac.uk
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Colorectal Cancer