Investigating microRNA levels in ultimate frisbee athletes after exercise
Investigation of MicroRNA-1 (miRNA-1) and MicroRNA-133a (miRNA-133a) Levels After Acute Neuromuscular Exercise in Ultimate Frisbee Athletes
This study tests how exercise affects certain tiny molecules in the saliva of ultimate frisbee athletes to see how their bodies respond and recover.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 34 (estimated) |
| Ages | 18 Years to 25 Years |
| Sex | All |
| Sponsor | Yeditepe University Academic / other |
| Locations | 1 site (Istanbul) |
| Trial ID | NCT06083610 on ClinicalTrials.gov |
What this trial studies
This clinical trial aims to explore how levels of microRNA-1 and microRNA-133a change in response to acute neuromuscular exercise in ultimate frisbee athletes. Participants will undergo a specific exercise regimen and provide saliva samples for analysis of these microRNAs before and after the exercise. The study seeks to determine the acute effects of exercise on these molecular markers, which are believed to play a role in muscle adaptation and recovery. By comparing the levels of these microRNAs, researchers hope to gain insights into the biological responses to exercise.
Who should consider this trial
Good fit: Ideal candidates for this study are healthy ultimate frisbee athletes who have not experienced any acute illnesses or orthopedic injuries in the past 12 weeks.
Not a fit: Patients with acute diseases, recent orthopedic injuries, or those regularly using medications or dietary supplements may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance our understanding of muscle adaptation to exercise, potentially leading to improved training methods for athletes.
How similar studies have performed: While the specific focus on ultimate frisbee athletes may be novel, previous studies have shown that microRNAs are significant in exercise adaptation, suggesting potential for success in this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Not suffering from an acute illness * Not having had an orthopedic injury in the last 12 weeks may prevent them from exercising * Volunteering to participate in the study Exclusion Criteria: * Presence of an acute disease * Having an orthopedic injury that may prevent exercise in the last 12 weeks * Regular use of medication and/or dietary supplements * Presence of a chronic \& systemic disease * Not volunteering to participate in the study
Where this trial is running
Istanbul
- Yeditepe University — Istanbul, Turkey (Recruiting)
Study contacts
- Principal investigator: Turgay İsbir, Prof. Dr. — Yeditepe University
- Study coordinator: Mehmet A Pekdaş, Research Assistant
- Email: alperen.pekdas@yeditepe.edu.tr
- Phone: 02165780000
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.