Clinical trial Recruiting at 1 site Observational

Investigating lymph node patterns in lung adenocarcinoma

Official title: Lymph Node Pathologic Grading Strategy: Under the Backdrop of the IASLC Grading System for Invasive Lung Adenocarcinoma - a Retrospective Cohort Study

Run by Fudan University · NCT06745830 · Data updated 2026-11-12

This study looks at how different patterns in lymph nodes from lung adenocarcinoma patients can help predict their health outcomes after surgery.

Quick facts

Study typeObservational
SexAll
Enrollment2998 (estimated)
SponsorFudan University
Academic / other
Locations1 site (Shanghai, Shanghai Municipality)
StatusRecruiting
StartedApril 10, 2024
Main results expectedDecember 30, 2024
Study endsApril 20, 2025
Registry record updatedDecember 20, 2024
Trial IDNCT06745830 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are patients with invasive lung adenocarcinoma who have undergone surgical resection.

Probably not a fit

Patients with adenocarcinoma in situ, minimally invasive adenocarcinoma, or other variants of adenocarcinoma may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to evaluate the prognostic significance of pathologic patterns in metastatic lymph nodes (mLNs) of patients with lung adenocarcinoma. By analyzing a retrospective cohort of patients who underwent surgical resection, the study seeks to determine how the percentage of high-grade patterns in mLNs correlates with patient outcomes. The research focuses on understanding the implications of various histologic patterns in mLNs and their potential impact on prognosis.

Why it matters

Potential benefit: If successful, this study could enhance the understanding of lung adenocarcinoma prognosis and improve patient management strategies.

How similar studies have gone: While the specific approach of this study may be novel, similar studies have explored the prognostic value of lymph node patterns in various cancers, indicating potential for meaningful insights.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

From January 2011 to September 2021, we consecutively collected patients with invasive LUAD who underwent surgical resection at the Department of Thoracic Surgery, Fudan University Shanghai Cancer Center.

Exclusion Criteria:

1. adenocarcinoma in situ, minimally invasive adenocarcinoma, invasive mucinous adenocarcinoma, and other variants of adenocarcinoma;
2. incomplete common driver mutation data;
3. unavailable pathologic slides.

Where it's running

  • Fudan University Shanghai Cancer Center
    Shanghai, Shanghai Municipality, China
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.