Investigating Lipid Levels and Pain After Breast Cancer Surgery
Study of Lipid Mediators in Chronic Postoperative Pain Following Breast Cancer Surgery
This study is testing if the levels of fats in the blood can help predict how much pain women will have after breast cancer surgery.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 300 (estimated) |
| Ages | 18 Years and up |
| Sex | Female |
| Sponsor | Université Catholique de Louvain Academic / other |
| Locations | 1 site (Brussels, Brussels Capital) |
| Trial ID | NCT06907810 on ClinicalTrials.gov |
What this trial studies
This interventional study aims to explore the relationship between lipid levels in blood samples and the intensity and duration of postoperative pain in women undergoing surgery for breast cancer. It will assess whether variations in circulating lipid mediators can predict chronic postoperative pain lasting more than three months. Additionally, the study will evaluate the activation of specific immune cells in the blood of participants. Women aged 18 and older with newly diagnosed breast cancer requiring surgical intervention will be enrolled.
Who should consider this trial
Good fit: Ideal candidates are women aged 18 and older who have been newly diagnosed with primary invasive or non-invasive breast cancer requiring surgical removal of the tumor.
Not a fit: Patients who are men, under 18 years old, pregnant, or have a history of major psychiatric disorders may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to better pain management strategies for women recovering from breast cancer surgery.
How similar studies have performed: While the specific approach of this study may be novel, similar studies investigating lipid mediators and pain have shown promising results in related fields.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Women older than 18 years * Newly diagnosed primary invasive or non-invasive breast cancer, requiring surgical excision of the tumor, with or without axillary surgery * Able to give informed consent Exclusion Criteria: * Men * Women aged less than 18 years * Pregnant women * History of major psychiatric disorders * Previous breast or axillary surgery, recurrent disease or detectable metastatic disease at the time of diagnosis * Unable to give informed consent
Where this trial is running
Brussels, Brussels Capital
- Cliniques universitaires Saint-Luc (UCLouvain) — Brussels, Brussels Capital, Belgium (Recruiting)
Study contacts
- Principal investigator: Mireille Alhouayek, PhD — Université Catholique de Louvain
- Study coordinator: Martine Berlière, MD, PhD
- Email: martine.berliere@saintluc.uclouvain.be
- Phone: 00327641075
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.