Investigating inflammation and insulin resistance in obese individuals

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study examines the role of resolution molecules in reducing inflammation and insulin resistance in human tissue samples from obese individuals. It aims to determine if these effects correlate with specific patient resolution phenotypes. Participants must have undergone gastric bypass surgery at least two years prior and have maintained a stable weight for six months. The study focuses on understanding the biological mechanisms underlying obesity-related complications.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* BMI 30-40 kg/m2
* Ptos (i.e. excess skin) \> 3 cm
* Patient underwent gastric bypass surgery \>2 years ago
* Patient has had a stable weight ≥6 months at the time of operation
* Patient does not smoke (min 6 weeks prior to surgery)

Exclusion Criteria:

* Patients who do not understand spoken and written Swedish
* American Society of Anesthesiologists (ASA) classification ≥ 3
* Neurological, orthopedic or rheumatologic injury or illness affecting physical ability
* Preoperatively known hernia requiring surgical operation
* Severe mental illness

Where it's running

• Sahlgrenska university hospital
  Gothenburg, Västra Götaland County, Sweden Recruiting

Study contacts

• Study coordinator: Emma Borgeson, PhD
• Email: emma.borgeson@wlab.gu.se
• Phone: +46313420000

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.