Clinical trial Recruiting at 1 site Observational Ages 18 and up

Investigating immune responses in allergic asthma

Official title: Innate Immunity in Allergic Asthma

Run by University of Central Florida · NCT06068335 · Data updated 2026-11-12

This study is trying to see if certain immune responses are linked to allergic asthma by testing how cells react to different allergens in people with allergies or asthma compared to healthy individuals.

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment100 (estimated)
SponsorUniversity of Central Florida
Academic / other
Locations1 site (Orlando, Florida)
StatusRecruiting
StartedOctober 18, 2021
Main results expectedJune 2025
Study endsJune 2025
Registry record updatedDecember 6, 2024
Trial IDNCT06068335 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates include adults aged 18 and older with either clinically diagnosed allergies or asthma, as well as healthy individuals without a history of allergic disease.

Probably not a fit

Patients who are pregnant, prisoners, or currently suffering from acute infections will not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to explore the relationship between a specific immune response, known as a type 2 signature, and allergic or asthmatic conditions. Researchers will stimulate cell lines with various allergens in a laboratory setting to identify patterns in cell surface receptor expression, pathway activation, and gene upregulation. The findings will help determine if these immune responses correlate with the presence of allergic diseases or asthma in individuals. The study will include healthy controls as well as participants with diagnosed allergies or asthma.

Why it matters

Potential benefit: If successful, this study could enhance our understanding of allergic asthma and lead to improved diagnostic and therapeutic strategies.

How similar studies have gone: While the specific approach of this study is novel, similar studies investigating immune responses in asthma have shown promising results.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Participants must be at least 18 years of age
* no history of allergic disease (healthy controls), have clinically diagnosed allergies, or have clinically diagnosed asthma.

Exclusion Criteria:

* Pregnant women and prisoners will be excluded from the study.
* Individuals currently suffering from any acute infections and those known to suffer from light-headedness will be excluded.

Where it's running

  • University of Central Florida
    Orlando, Florida, United States
    Recruiting

Study contacts

  • Principal investigator: Justine T Tigno-Aranjuez, PhD — University of Central Florida
  • Study coordinator: Amoy Fraser, PhD, CCRP, PMP
  • Email: amoy.fraser@ucf.edu
  • Phone: 4072668742

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.