Investigating how serum calcium levels affect pain after abdominal surgery
Official title: The Effect of Serum Calcium Levels on Postoperative Pain in Patients Undergoing Abdominal Surgery: A Prospective Observational Study
Run by The Second Affiliated Hospital of Chongqing Medical University · NCT06957158 · Data updated 2026-11-12
This study is testing if changes in calcium levels in the blood can affect how much pain people feel after having abdominal surgery.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years to 70 Years |
| Sex | All |
| Enrollment | 350 (estimated) |
| Sponsor | The Second Affiliated Hospital of Chongqing Medical University Academic / other |
| Locations | 1 site (Chongqing, Chongqing Municipality) |
| Status | Recruiting |
| Started | July 2025 |
| Main results expected | December 2025 |
| Study ends | December 2025 |
| Registry record updated | June 27, 2025 |
| Trial ID | NCT06957158 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults aged 18-70 who are undergoing elective abdominal surgery and are classified as ASA I-III.
✕Probably not a fit
Patients with severe diseases, chronic pain conditions, or those requiring intensive care post-surgery may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This prospective observational study examines the relationship between serum calcium levels and postoperative pain in patients undergoing elective abdominal surgery. Researchers will measure total serum calcium and ionized calcium levels before and after surgery, while also recording pain scores at various time points using a numerical rating scale (NRS). The goal is to determine if fluctuations in serum calcium levels can be a risk factor for experiencing postoperative pain.
Why it matters
Potential benefit: If successful, this study could lead to improved pain management strategies for patients after surgery.
How similar studies have gone: While there have been studies exploring postoperative pain management, the specific focus on serum calcium levels is relatively novel and has not been extensively tested.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Aged 18-70 years old * American Society of Anesthesiologists Classification I-III * Patients undergoing elective abdominal surgery under general anesthesia * Patients participate voluntarily and sign an informed consent form Exclusion Criteria: * Patients with a history of severe disease * Patients with chronic preoperative pain and/or long-term analgesic use * Patients with hearing disorders or verbal communication difficulties * Patients with psychiatric disorders or cognitive dysfunction * Patients requiring mechanical ventilation or ICU admission after surgery * Patients with a history of substance or alcohol abuse Patients who could not cooperate with the study for any reason
Where it's running
-
The Second Affiliated Hospital of Chongqing Medical University
Chongqing, Chongqing Municipality, China Recruiting
Study contacts
- Study coordinator: Guangyou Duan, PhD
- Email: duangy@hospital.cqmu.edu.cn
- Phone: +86 183 2337 6014
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.