Investigating how reflux affects voice quality
The Voice of Reflux: Typical Vocal Biomarkers in Patients With Gastroesophageal Reflux Disease
Insel Gruppe AG, University Hospital Bern · NCT06495606
This study is testing how gastroesophageal reflux and laryngopharyngeal reflux affect the quality of voice in adults over 18.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 94 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Insel Gruppe AG, University Hospital Bern (other) |
| Locations | 1 site (Bern) |
| Trial ID | NCT06495606 on ClinicalTrials.gov |
What this trial studies
This observational study examines the impact of gastroesophageal reflux disease (GERD) and laryngopharyngeal reflux disease (LPRD) on voice quality. Participants over the age of 18 will provide voice samples and complete questionnaires while undergoing standard reflux diagnostics. The study aims to identify typical voice changes associated with reflux conditions, which may help in understanding the relationship between reflux and vocal health.
Who should consider this trial
Good fit: Ideal candidates for this study are adults over 18 who are undergoing diagnostic evaluation for gastroesophageal reflux.
Not a fit: Patients with prior laryngopharyngeal surgery or those with diseases that alter voice quality may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved diagnosis and management of voice-related issues in patients suffering from reflux diseases.
How similar studies have performed: While there is existing research on reflux and voice changes, this study aims to provide specific insights into vocal biomarkers, making it a novel approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age above 18 * Informed consent * Undergoing gastroesophageal reflux diagnostic according to the current standard * Basic reading skills in German or English Exclusion Criteria: * Age below 18 * No basic reading skills in German or English * Diseases with altered voice * Laryngopharyngeal surgery or interventions in the past
Where this trial is running
Bern
- Universitätsspital Inselspital Bern — Bern, Switzerland (RECRUITING)
Study contacts
- Principal investigator: Yves Borbély, Dr. med. — Insel Gruppe AG, University Hospital Bern
- Study coordinator: Nina Moser, Dr. med.
- Email: nina.moser@insel.ch
- Phone: +41316323723
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: GERD Gastroesophageal Reflux Disease, Laryngopharyngeal Reflux Disease, GERD, LPRD, Reflux, Voice, Vocal Biomarker