Investigating hip muscle thickness and strength in prosthesis users with leg amputation

The Evaluation of the Relationship Between Thicknesses and Isokinetic Strength of Hip Flexor and Extensor Muscles in Patients With Unilateral Traumatic Transfemoral Amputation

Observational Gaziler Physical Medicine and Rehabilitation Education and Research Hospital · NCT05827744

This study is trying to see if measuring the thickness of hip muscles can help us understand their strength in people who have had a leg amputated above the knee.

Quick facts

Study typeObservational
Enrollment27 (estimated)
Ages18 Years to 65 Years
SexMale
SponsorGaziler Physical Medicine and Rehabilitation Education and Research Hospital Academic / other
Locations1 site (Ankara)
Trial IDNCT05827744 on ClinicalTrials.gov

What this trial studies

This observational study aims to explore the relationship between the thickness of hip flexor and extensor muscles, as measured by ultrasonography, and the strength of hip flexion and extension in individuals with unilateral traumatic transfemoral amputation. Participants will undergo isokinetic evaluations and ultrasonographic assessments to determine how muscle thickness correlates with functional strength and other clinical parameters. The findings may help establish ultrasonography as a valuable tool for monitoring changes in hip muscle function in this patient population.

Who should consider this trial

Good fit: Ideal candidates are individuals aged 18-65 who have undergone unilateral traumatic transfemoral amputation and have been using a prosthesis for at least 3 months.

Not a fit: Patients with bilateral lower extremity amputations or those with neurological, cardiovascular, or pulmonary diseases that affect walking performance may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could enhance rehabilitation strategies for patients with leg amputations by providing insights into muscle function and strength.

How similar studies have performed: While this study focuses on a specific patient population, similar approaches using ultrasonography to assess muscle function have shown promise in other contexts.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Aged between 18-65
* The time elapsed after amputation \> 6 months
* Using prosthesis for at least 3 months
* Being able to walk without an assistive device

Exclusion Criteria:

* Bilateral lower extremity amputation
* Presence of neurological, cardiovascular, and pulmonary disease that may affect walking performance

Where this trial is running

Ankara

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Amputation, Traumaticamputationhip flexorship extensors
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.