Clinical trial Recruiting at 1 site Observational Ages 18 and up

Investigating heart issues in COPD patients during hospital stays

Official title: Prospective Observational Study of Myocardial Stunning in Patients Hospitalized for Exacerbation of Chronic Obstructive Pulmonary Disease

Run by Sahlgrenska University Hospital · NCT06597331 · Data updated 2026-11-12

This study is trying to see if sudden worsening of COPD can cause heart problems in hospitalized patients and how it affects their recovery.

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment200 (estimated)
SponsorSahlgrenska University Hospital
Academic / other
Locations1 site (Gothenburg, Region Västra Götaland)
StatusRecruiting
StartedSeptember 23, 2024
Main results expectedDecember 31, 2027
Study endsSeptember 1, 2028
Registry record updatedSeptember 17, 2026
Trial IDNCT06597331 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are adults aged 18 and older who are hospitalized for acute exacerbations of chronic obstructive pulmonary disease.

Probably not a fit

Patients with a history of acute myocardial infarction or significant pre-existing heart conditions may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to explore how acute exacerbations of chronic obstructive pulmonary disease (AE-COPD) may trigger Takotsubo-stunning in hospitalized patients and the subsequent impact on their health outcomes. It will assess the incidence of Takotsubo-stunning among these patients and compare the risk of in-hospital acute heart failure between those with and without this condition. The study will involve adult patients admitted for AE-COPD at Sahlgrenska University Hospital in Gothenburg, Sweden, and will collect data within 72 hours of their admission.

Why it matters

Potential benefit: If successful, this study could improve the diagnosis and management of heart complications in COPD patients, potentially leading to better patient outcomes.

How similar studies have gone: While the specific approach of this study may be novel, there is existing literature suggesting a link between COPD exacerbations and Takotsubo syndrome, indicating potential for meaningful insights.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Adult patients (≥ 18 years old) admitted to hospital ward for AE-COPD
* Inclusion within 72 hours of admission,
* Written informed consent

Exclusion Criteria:

* Prior acute myocardial infarction or known pre-existing persistent regional wall motion abnormality or left ventricular dysfunction (left ventricular ejection fraction \[LVEF\] \<50%)
* Expected inability to comply with the protocol (e.g. dementia)

Where it's running

  • Department of Emergency Medicine and Geriatrics, Sahlgrenska University Hospital/S
    Gothenburg, Region Västra Götaland, Sweden
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.